Evidence map›Paper›PMID 42684105›Full record

ArticleTranslational vision science & technology2026

BlinkNet-Q: A Deep Learning-Based Software for Real-Time Blink Rate Quantification and Incomplete-Blink Pattern Recognition.

Zhiqiang Xu, Jiahui Shen, Anran Liu, Jun Wen, Hongwen Li, Pedro Arriola-Villalobos, Minhui Wu, Jia Qu, Fan Lu, Liang Hu

Abstract read
In one paragraph

Article in Translational vision science & technology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zhiqiang XuNational Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, China.
Jiahui ShenDepartamento de Inmunología, Oftalmología y ORL, Facultad de Medicina, Universidad Complutense de Madrid (UCM), IdISSC, Madrid, Spain.
Anran LiuNational Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, China.
Jun WenNational Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, China.
Hongwen LiNational Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, China.
Pedro Arriola-VillalobosServicio de Oftalmología, Hospital Clínico San Carlos, Departamento de Inmunología, Oftalmología y ORL, Facultad de Medicina, Universidad Complutense de Madrid (UCM), IdISSC, Madrid, Spain.
Minhui WuNational Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, China.
Jia QuNational Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, China.
Fan LuNational Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, China.
Liang HuNational Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To develop and validate a dual deep learning model (DLM)-based software (BlinkNet-Q) for near real-time quantification of blink rate and incomplete blinks using standard red-green-blue video. Methods: BlinkNet-Q integrated two DLMs: DLM-1 classified open-eye versus complete-blink frames, and DLM-2 differentiated complete from incomplete blinks. This proof-of-concept technical validation study included separate model development and independent testing cohorts. The development cohort comprised 15 participants (30 eyes), yielding 2953 annotated frames for training and internal validation, with participant-level data splitting. The testing cohort included 39 participants (39 eyes) and was used for final evaluation of the BlinkNet-Q. Frame-wise analysis with computer vision-based eye localization enabled automated blink quantification. Performance was assessed using classification metrics, regression-based metrics, intraclass correlation coefficient (ICC), and Bland-Altman analysis. Results: DLM-1 achieved an area under the curve (AUC) of 0.989 (95% confidence interval [CI], 0.932-0.993), and DLM-2 reached an AUC of 0.884 (95% CI, 0.854-0.963). The BlinkNet-Q showed strong agreement with manual counting for blink rate (ICC = 0.973; R² = 0.948; mean absolute error [MAE] = 1.262 blinks/min) and incomplete-blink ratio (ICC = 0.937; R² = 0.876; MAE = 0.059), with small mean biases under standardized recording conditions. Conclusions: BlinkNet-Q demonstrated the technical feasibility of automated blink rate and incomplete-blink quantification under standardized recording conditions, supporting its potential as a software prototype for blink assessment. Further external validation in diverse clinical populations is needed before clinical implementation. Translational Relevance: BlinkNet-Q may support future development of accessible, camera-based blink assessment tools for ocular surface evaluation.

Indexed as

BlinkingDeep LearningPattern Recognition, AutomatedSoftwareAdultFemaleHumansMaleReproducibility of ResultsVideo Recording

Identifiers

PMID42684105
PMCPMC13549406

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.