Observational studyIndian journal of pharmacology2026
Assessment of antimicrobial use among patients admitted to a tertiary care hospital: A prospective observational study using World Health Organization AWaRe and Indian Council of Medical Research guidelines.
Observational study in Indian journal of pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAntimicrobial resistance has emerged as a global challenge to human health, primarily due to inappropriate use. The ICMR reports revealed that there is sustained rise of AMR in India.
objectiveThe objective of this study was to evaluate the prescribing pattern of antimicrobials and rationality of empiric antimicrobial use in a tertiary care hospital.
methodA prospective observational study, approved by the Institutional Ethical Committee (IEC) was conducted for a period of one year from July 2023 to June 2024 among the admitted patients of the hospital. The prescribing pattern was assessed in accordance with AWaRe classification and prescribing indicators by the World Health Organization. Rational use of empiric therapy was assessed as per the ICMR 2022 guidelines.
resultsA total of 653 antimicrobials were prescribed to 289 patients and maximum antimicrobials were from Watch category (55.7%), followed by Access (40.4%), and Reserve category (2.3%). The respiratory tract infection was the most common indication to start empiric antimicrobial therapy. The empiric therapy was appropriate for 80.3% patients as per the ICMR guidelines. The observed deviations were the empiric use of amikacin for bone & joint infection, duplicate beta lactam therapy, 3rd generation cephalosporins for uncomplicated urinary tract infection, the use of Reserve antibiotic-linezolid, and the use of piperacillin/tazobactam for sepsis patients.
conclusionThere is a need to strengthen the antimicrobial stewardship program by adhering to the national guidelines in the hospital settings, to prevent antimicrobial misuse and resistance. The use of Assess category should be encouraged, Watch category should be used under proper monitoring and the use of Reserve antimicrobials as an empiric therapy should be avoided.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.