Evidence map›Paper›PMID 42683598›Full record

ArticleMicrobial biotechnology2026

Design of a Bacteriophage-Based Product for Biocontrol of Fire Blight and Black Rot.

Gloria Vique, Pedro Blanco-Picazo, Aina Trenchs, Maria Dolores Ramos-Barbero, Maria Isern, Pablo Quirós, Sergio Atares, Ignasi Salaet, Laura Sala-Comorera, Lorena Rodríguez-Rubio and 1 more

Abstract read
In one paragraph

Article in Microbial biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Gloria ViqueDepartament de Genètica, Microbiologia i Estadística, Universitat de Barcelona, Barcelona, Spain.ORCID https://orcid.org/0000-0002-0584-7302
Pedro Blanco-PicazoDepartament de Genètica, Microbiologia i Estadística, Universitat de Barcelona, Barcelona, Spain.ORCID https://orcid.org/0000-0002-0890-4165
Aina TrenchsDepartament de Genètica, Microbiologia i Estadística, Universitat de Barcelona, Barcelona, Spain.ORCID https://orcid.org/0009-0002-0223-5017
Maria Dolores Ramos-BarberoDepartament de Genètica, Microbiologia i Estadística, Universitat de Barcelona, Barcelona, Spain.ORCID https://orcid.org/0000-0001-7893-8320
Maria IsernDepartament de Genètica, Microbiologia i Estadística, Universitat de Barcelona, Barcelona, Spain.ORCID https://orcid.org/0009-0000-1393-2139
Pablo QuirósDepartamento de I+D+i de Fertinagro Biotech S.L, Polígono Industrial La Paz, Teruel, Spain.ORCID https://orcid.org/0000-0001-5770-1375
Sergio AtaresDepartamento de I+D+i de Fertinagro Biotech S.L, Polígono Industrial La Paz, Teruel, Spain.ORCID https://orcid.org/0000-0003-0868-274X
Ignasi SalaetDepartamento de I+D+i de Fertinagro Biotech S.L, Polígono Industrial La Paz, Teruel, Spain.ORCID https://orcid.org/0000-0002-4672-7147
Laura Sala-ComoreraDepartament de Genètica, Microbiologia i Estadística, Universitat de Barcelona, Barcelona, Spain.ORCID https://orcid.org/0000-0001-6507-5677
Lorena Rodríguez-RubioDepartament de Genètica, Microbiologia i Estadística, Universitat de Barcelona, Barcelona, Spain.ORCID https://orcid.org/0000-0002-7846-4791
Maite MuniesaDepartament de Genètica, Microbiologia i Estadística, Universitat de Barcelona, Barcelona, Spain.ORCID https://orcid.org/0000-0001-5549-1394

Funding

ERDF/EUGeneralitat de CatalunyaInstitució Catalana de Recerca i Estudis AvançatsMICIU/AEI CPP2023-010671Ministerio de Universidades
6 · The paper itself

Abstract

Controlling phytopathogenic bacteria is essential for safeguarding crops and minimizing economic losses in agriculture. Although chemical pesticides are effective, they have adverse effects on ecosystems, beneficial organisms such as pollinators, and natural pathogen predators, creating a need for sustainable alternatives. Bacteriophages ɸEF1 and ɸEF2 (infecting Erwinia amylovora, the fire blight pathogen), and ɸXF1 (targeting Xanthomonas campestris, the black rot pathogen) have shown promise as biocontrol agents in vitro and in vivo. However, to be effective in the field these phages must maintain infectivity during storage and environmental exposure. We evaluated their stability under varying pH, temperature, UV and sunlight conditions and assessed various photoprotective additives. The phages remained infectious for up to 3 months at 4°C and 20°C and pH 7-9, but were inactivated at pH 3 and 37°C. UV rapidly inactivated the phages, but their stability was significantly enhanced by adding photoprotectants like Amino 22% or CaCO

Indexed as

BacteriophagesBiological Control AgentsErwinia amylovoraPest Control, BiologicalPlant DiseasesXanthomonasHydrogen-Ion ConcentrationTemperatureUltraviolet RaysVirus InactivationBiological Control AgentsbacteriophagesbiocontrolErwinialysispersistencephotoprotectantXanthomonas

Identifiers

PMID42683598
PMCPMC13535983

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.