Evidence map›Paper›PMID 42683594›Full record

ReviewMacromolecular bioscience2026

Research Progress on Antibacterial Strategies of pH-Responsive Hydrogel Dressings in Chronic Wound Management.

Long Jiang, Hui You, Wenqing Yu, Jiawei Li, Liwei Hu, Huixu Xie

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Macromolecular bioscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Long JiangState Key Laboratory of Oral Diseases, National Center For Stomatology, National Clinical Research Center for Oral Diseases, Department of Head and Neck Oncology Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, China.ORCID https://orcid.org/0009-0009-7572-850X
Hui YouState Key Laboratory of Oral Diseases, National Center For Stomatology, National Clinical Research Center for Oral Diseases, Department of Head and Neck Oncology Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, China.
Wenqing YuState Key Laboratory of Oral Diseases, National Center For Stomatology, National Clinical Research Center for Oral Diseases, Department of Head and Neck Oncology Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, China.
Jiawei LiState Key Laboratory of Oral Diseases, National Center For Stomatology, National Clinical Research Center for Oral Diseases, Department of Head and Neck Oncology Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, China.
Liwei HuState Key Laboratory of Oral Diseases, National Center For Stomatology, National Clinical Research Center for Oral Diseases, Department of Head and Neck Oncology Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, China.
Huixu XieState Key Laboratory of Oral Diseases, National Center For Stomatology, National Clinical Research Center for Oral Diseases, Department of Head and Neck Oncology Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, China.

Funding

Clinical Research Project of West China School of Stomatology, Sichuan University LCYJ-QN-202502National Natural Science Foundation of China 82370977
6 · The paper itself

Abstract

Chronic wound healing is a dynamic and complex physiological process. Bacterial biofilms and antibiotic resistance seriously impede the repair of chronic wounds. Traditional dressings cannot respond to the characteristic acidic microenvironment (pH 4.5-6.5) of infected wounds, making it difficult to achieve targeted antibacterial effects. pH-responsive hydrogels can precisely release antibacterial components through acid triggering. They can specifically recognize the changes in the acidic micro environment created by bacterial metabolites, and then achieve the on-demand release of functional components, showing great potential in chronic wound management. This paper systematically reviews the dynamic cross-linking mechanism of pH-responsive hydrogel dressings, focuses on summarizing their antibacterial strategies, summarizes their functional characteristics in controlling bacterial infections, promoting tissue repair, and implementing wound monitoring, and prospectively discusses their clinical translation potential.

Indexed as

Anti-Bacterial AgentsBandagesHydrogelsWound HealingAnimalsBacteriaBiofilmsHumansHydrogen-Ion ConcentrationAnti-Bacterial AgentsHydrogelsantibacterial strategybiomaterialchronic woundpH‐responsive hydrogelwound healing

Identifiers

PMID42683594
PMCPMC13535895

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.