ArticleJournal of surgical case reports2026
Post-operative bilateral anterior uveitis: a rare case of ocular complication associated with anti-adhesion agent use in obstetric and gynaecologic surgery.
Article in Journal of surgical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Drug-induced uveitis is a rare and often under-recognised entity. We present a rare case series of bilateral anterior uveitis associated with Mediclore, a thermosensitive anti-adhesion agent composed of gelatine, chitosan, and poloxamer, used in obstetric and gynaecologic surgery. Nine female patients aged 30-51 were included; five had Caesarean sections, and four had total abdominal hysterectomy with bilateral salpingo-oophorectomy (one patient also had an appendectomy). Ocular symptoms started on the first/second postoperative day. Initial visual acuity (VA) was between 0.5 and 1.0; intraocular pressure was normal; and inflammation was mild, anterior, and frequently bilateral. Topical corticosteroids (dexamethasone, prednisolone acetate, or fluorometholone) and mydriatics were prescribed. Active infection screening was ruled out. All patients demonstrated remission with a VA of 1.0 and no persistent inflammation. Even though topical medication gave favourable results, clinicians should be aware of this potential association, ensure appropriate screening to exclude mimickers, and counsel patients accordingly.
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