Evidence map›Paper›PMID 42683255›Full record

ArticleERJ open research2026

Managing multimorbidity in severe asthma: comparison of resources and perspectives between severe asthma specialists and general respiratory physicians across Europe.

Dace Matīsa, Aruna T Bansal, Saša Rink, Anna Freeman, Betty Frankemölle, Mehar Singh, Jacob K Sont, Apostolos Bossios, Ben Ainsworth, Michael Hyland and 56 more

Abstract read
In one paragraph

Article in ERJ open research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

66 authors.

Dace MatīsaPauls Stradiņš Clinical University Hospital, Riga, Latvia.ORCID https://orcid.org/0009-0003-2113-6169
Aruna T BansalAcclarogen Ltd, St John's Innovation Centre, Cambridge, UK.
Saša RinkDepartment of Pulmonary Diseases and Allergy, University Medical Centre Ljubljana, Ljubljana, Slovenia.
Anna FreemanSchool of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.
Betty FrankemölleEuropean Lung Foundation, Sheffield, UK.
Mehar SinghEuropean Lung Foundation, Sheffield, UK.
Jacob K SontDepartment of Biomedical Data Sciences, Medical Decision Making, Leiden University Medical Centre, Leiden, The Netherlands.
Apostolos BossiosKarolinska Severe Asthma Centre, Department of Respiratory Medicine and Allergy, Karolinska University Hospital, Stockholm, Sweden.ORCID https://orcid.org/0000-0002-0494-2690
Ben AinsworthSchool of Psychology, Faculty of Environmental and Life Sciences, University of Southampton, Southampton, UK.
Michael HylandSchool of Psychology, University of Plymouth, Plymouth, UK.
Rekha ChaudhuriSchool of Infection and Immunity, University of Glasgow, Glasgow, UK.
Florin MihaltanNational Institute of Pneumology, Bucharest, Romania.
Antonio SpanevelloDepartment of Cardiopulmonary Rehabilitation, Istituti Clinici Scientifici Maugeri IRCCS, Tradate, Italy.
Enrico HefflerPersonalized Medicine, Asthma and Allergy, IRCCS Humanitas Research Hospital, Rozzano, Italy.
Ian AdcockNational Heart & Lung Institute, Imperial College London, London, UK.ORCID https://orcid.org/0000-0003-2101-8843
Martina ZappaDepartment of Cardiopulmonary Rehabilitation, Istituti Clinici Scientifici Maugeri IRCCS, Tradate, Italy.ORCID https://orcid.org/0000-0001-8443-5316
Giorgio Walter CanonicaPersonalized Medicine, Asthma and Allergy, IRCCS Humanitas Research Hospital, Rozzano, Italy.ORCID https://orcid.org/0000-0001-8467-2557
Guy BrusselleDepartment of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium.ORCID https://orcid.org/0000-0001-7021-8505
Arnaud BourdinDepartment of Respiratory Diseases, Montpellier University Hospital, Arnaud de Villeneuve Hospital, Montpellier, France.ORCID https://orcid.org/0000-0002-4645-5209
Giulia Anna Maria Luigia CostanzoDepartment of Medical Science and Public Health, University of Cagliari, Cagliari, Italy.
Ildiko HorvathNational Koranyi Institute of Pulmonology, Budapest, Hungary.
Dóra LúðvíksdóttirLandspitali University Hospital, Reykjavik, Iceland.
Stefania PrincipeAmsterdam University Medical Centre, Amsterdam, The Netherlands.
Peter KopačMedical Faculty, University of Ljubljana, Ljubljana, Slovenia.
Cláudia Chaves LoureiroPulmonology Unit, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.ORCID https://orcid.org/0000-0003-0438-6126
Arne EgestenDepartment of Clinical Sciences Lund, Respiratory Medicine, Allergology, and Palliative Medicine, Lund University, Lund, Sweden.
Stephanie KornThoraxklinik Heidelberg, University of Heidelberg, Heidelberg, Germany.ORCID https://orcid.org/0009-0001-2239-5029
Konstantinos Samitas7th Respiratory Department and Asthma Centre, Athens Chest Hospital, Athens, Greece.
Marcus ButlerUniversity College Dublin, Dublin, Ireland.ORCID https://orcid.org/0000-0003-2026-7709
Joerg LeuppiUniversity Institute of Internal Medicine, Cantonal Hospital Baselland, Liestal, Switzerland.
Edin JusufovicDepartment for Internal Medicine, Faculty of Medicine, University in Tuzla, Tuzla, Bosnia and Herzegovina.
Felix WantkeFloridsdorf Allergy Center, Vienna, Austria.
Shane HanonUZ Brussels/Vrije Universiteit Brussel, Brussels, Belgium.ORCID https://orcid.org/0000-0002-1413-7927
Fabienne JaunUniversity Institute of Internal Medicine, Cantonal Hospital Baselland, Liestal, Switzerland.ORCID https://orcid.org/0000-0002-1229-2181
Virginija Kalinauskaite-ZukauskeDepartment of Pulmonology, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Sanja Dimic-JanjicFaculty of Medicine, University of Belgrade, Belgrade, Serbia.ORCID https://orcid.org/0000-0001-9989-3862
Graham RobertsThe David Hide Asthma and Allergy Research Centre, St Mary's Hospital, Newport, UK.ORCID https://orcid.org/0000-0003-2252-1248
Sanja HromisInstitute for Pulmonary Diseases of Vojvodina, Sremska Kamenica, Serbia.ORCID https://orcid.org/0000-0001-6132-1551
Branislava MilenkovicFaculty of Medicine, University of Belgrade, Belgrade, Serbia.
Judit Varkonyi-SeppClinical Health Psychology Department, Hampshire and Isle of Wight Healthcare NHS Foundation Trust/University Hospital Southampton NHS Foundation Trust, Southampton, UK.
Ozlem GokselDepartment of Pulmonary Medicine, Division of Immunology and Allergy, Laboratory of Occupational/Environmental Respiratory Diseases and Asthma, Ege University Faculty of Medicine, İzmir, Türkiye.
Ana Margarida PereiraRISE-Health, MEDCIDS, Department of Community Medicine, Information and Health Decision Sciences, and Faculty of Medicine, University of Porto, Porto, Portugal.
Ratko DjukanovicSchool of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.
Angela RizziUOSD Allergologia e Immunologia Clinica. Dipartimento Scienze Mediche e Chirurgiche, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.
Marco CaminatiDepartment of Medicine, University of Verona, Verona, Italy.
Ruihua HouSchool of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.ORCID https://orcid.org/0000-0001-6127-1478
Anamarija ŠtajduharClinic for pulmonary diseases Jordanovac, University Hospital Centre Zagreb, Zagreb, Croatia.
Dóra ParóczaiDepartment of Pulmonology, University of Szeged, Szeged, Hungary.
Luisa BrussinoAllergy and Immunology Unit, Department of Medical Sciences, University of Turin, Turin, Italy.
Liam G HeaneyQueens University Belfast, Belfast, UK.
Hans Michael HaitchiSchool of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.ORCID https://orcid.org/0000-0001-8603-302X
Matteo BonniniNational Heart & Lung Institute, Imperial College London, London, UK.
Kristina BieksieneDepartment of Pulmonology, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Ebru DamadogluDepartment of Pulmonology, Division of Allergy and Clinical Immunology, Hacettepe University, School of Medicine, Ankara, Türkiye.
Valentyna YasinskaKarolinska Severe Asthma Centre, Department of Respiratory Medicine and Allergy, Karolinska University Hospital, Stockholm, Sweden.ORCID https://orcid.org/0000-0002-1379-1265
Bilun GemiciogluDepartment of Pulmonary Diseases, Cerrahpasa Faculty of Medicine, Istanbul University-Cerrahpasa, Istanbul, Türkiye.ORCID https://orcid.org/0000-0001-5953-4881
Sanja Popović GrleUniversity Hospital Centre Zagreb, KBCZ, Clinical Center for Pulmonary Diseases Jordanovac, Zagreb, Croatia.
Anneke Ten BrinkeMedical Centre Leeuwarden, Leeuwarden, The Netherlands.
Zsuzsanna CsomaNational Koranyi Institute of Pulmonology, Budapest, Hungary.
Iveta KroičaRiga East University Hospital, Riga, Latvia.
Piotr KunaDepartment of Internal Medicine, Asthma and Allergy, Medical University of Lodz, Lodz, Poland.
Celeste PorsbjergDepartment of Respiratory and Infectious Diseases, Bispebjerg Hospital, Copenhagen, Denmark.
Hilary HodgeEuropean Lung Foundation, Sheffield, UK.
Florence SchleichRespiratory Medicine, CHU of Liege, Liege, Belgium.ORCID https://orcid.org/0000-0002-2678-1373
Sabina SkrgatDepartment of Pulmonary Diseases and Allergy, University Medical Centre Ljubljana, Ljubljana, Slovenia.
Ramesh J KurukulaaratchySchool of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Multimorbidity refers to the presence of multiple coexisting conditions, but is often underappreciated in the context of severe asthma (SA) management. We sought to identify differences in approaches to multimorbidity management in SA, variability in access to multidisciplinary team (MDT) resources, and whether physician perspectives on multimorbidity differ between SA specialists and general respiratory physicians. Methods: The Severe Heterogeneous Asthma Registry, Patient-centred (SHARP) Clinical Research Collaboration circulated an online physician survey Results: 495 responses from 25 European countries included 48% SA specialists and 52% general respiratory physicians. SA specialists had more experience with SA patients (20% were seeing >60 patients per month) compared to general respiratory physicians. SA specialists had greater access to multidisciplinary care - including better access to MDTs, allied health professionals and referrals to external specialists, and therefore more routinely assessed comorbidities and considered them greater influences on their practice. They also considered multimorbidity to a greater degree and rated its impact on their patients' asthma outcomes (and general health outcomes) as more substantial. Conclusions: Alongside more experience of treating SA, SA specialists have increased awareness of multimorbidity and better resources to manage it. However, access to MDTs remains a significant gap for both SA specialists and general respiratory physicians. Furthermore, both groups identified a high need for further education and training about multimorbidity. These findings highlight key areas for improvement in clinical practice, resources and training.

Identifiers

PMID42683255
PMCPMC13531303

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.