Evidence map›Paper›PMID 42683232›Full record

ArticleFrontiers in pediatrics2026

How much sweating is enough? Predicting thermoregulatory capacity in patients with ectodermal dysplasia based on a minimal pilocarpine-induced sweat volume.

Anja Bachfischer, Carola Berking, Smail Hadj-Rabia, Umberto Simeoni, Anna L David, Holm Schneider

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anja BachfischerCenter for Ectodermal Dysplasias, University Hospital Erlangen, Erlangen, Germany.
Carola BerkingDepartment of Dermatology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Smail Hadj-RabiaDepartment of Dermatology, Reference Centre for Genodermatoses and Rare Skin Diseases, Hopital Necker-Enfants malades, University of Paris-Cité, Paris, France.
Umberto SimeoniDivision of Pediatrics, University of Lausanne, Lausanne, Switzerland.
Anna L DavidEGA Institute for Women's Health, University College London, London, United Kingdom.
Holm SchneiderCenter for Ectodermal Dysplasias, University Hospital Erlangen, Erlangen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Pathogenic Methods: In patients with hypomorphic Results: We studied a rare cohort of individuals with hypomorphic Conclusion: A sweat volume ≥15 µL, measured in a standard test on male infants using the Macroduct system, appears to indicate normal thermoregulatory capacity in the European climate.

Indexed as

clinical trial endpointhypohidrotic ectodermal dysplasiahypomorphic mutationSweat volumethermoregulation

Identifiers

PMID42683232
PMCPMC13532539

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.