ArticleInternational archives of otorhinolaryngology2026
Early Postoperative PTH Determination as Predictor for Post-Thyroidectomy Hypocalcemia.
Article in International archives of otorhinolaryngology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors.
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Abstract
Objective: Post-thyroidectomy hypocalcemia is a major complication following total thyroidectomy. This study aimed to evaluate early postoperative parathyroid hormone (PTH) measurement as a predictor of hypocalcemia after thyroidectomy and its impact on same-day discharge. Methods: This study combined a prospective IRB-approved correlation study of 60 patients who underwent total thyroidectomy with a meta-analysis of 5 observational studies. Results: Using Pearson Correlation Coefficient correlation, there was a significant positive correlation between PTH measured 1H after surgery with 4 H PTH (PCC = 0.787) and 4H Ionized Ca (PCC = 0.642). The sensitivity of early PTH measurement (cutoff < 14 pg/mL) for detecting hypocalcemia was 100%, with an AUC of 0.977 (95% CI: 0.565-1.0). Meta-analysis of previous studies confirmed a strong positive association between early PTH and late measurements. Conclusions: Early PTH measurement at 1 hour after surgery is a highly sensitive tool for detecting post-thyroidectomy hypocalcemia, which may help reduce hospital stay following thyroidectomy.
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