Evidence map›Paper›PMID 42683070›Full record

ArticleASM case reports2026

Detection and genomic characterization of a travel-associated ECSA lineage chikungunya virus infection in Mexico.

Daniel Canul Canul, K Jacqueline Ciau-Carrillo, J Reyes Canche Pech, Cesar Cañas-Alamilla, Jesús Kú-Cachón, Ana Osorio-Medrano, Maria E Lopez-Novelo, Igrid García González, James Earnest, Daniel Limonta and 16 more

Abstract readCase Reports
In one paragraph

Article in ASM case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Daniel Canul Canul *Universidad Autónoma de Yucatán, Centro de Investigaciones Regionales Dr. Hideyo Noguchi, Merida, Yucatan, Mexico.ORCID https://orcid.org/0009-0004-5792-6960
K Jacqueline Ciau-Carrillo *Universidad Autónoma de Yucatán, Centro de Investigaciones Regionales Dr. Hideyo Noguchi, Merida, Yucatan, Mexico.ORCID https://orcid.org/0009-0009-7161-541X
J Reyes Canche PechBiomédicos de Mérida, Laboratorios Clínicos, Mérida, Yucatan, México.
Cesar Cañas-AlamillaUniversidad Autónoma de Yucatán, Centro de Investigaciones Regionales Dr. Hideyo Noguchi, Merida, Yucatan, Mexico.
Jesús Kú-CachónUniversidad Autónoma de Yucatán, Centro de Investigaciones Regionales Dr. Hideyo Noguchi, Merida, Yucatan, Mexico.ORCID https://orcid.org/0009-0008-5865-285X
Ana Osorio-MedranoUniversidad Autónoma de Yucatán, Centro de Investigaciones Regionales Dr. Hideyo Noguchi, Merida, Yucatan, Mexico.ORCID https://orcid.org/0009-0008-9379-3738
Maria E Lopez-NoveloBiomédicos de Mérida, Laboratorios Clínicos, Mérida, Yucatan, México.
Igrid García GonzálezBiomédicos de Mérida, Laboratorios Clínicos, Mérida, Yucatan, México.
James EarnestBurnett School of Biomedical Sciences, University of Central Florida, Orlando, Florida, USA.ORCID https://orcid.org/0000-0002-5904-8733
Daniel LimontaBurnett School of Biomedical Sciences, University of Central Florida, Orlando, Florida, USA.ORCID https://orcid.org/0000-0002-5128-6542
Norma Pavia-RuzUniversidad Autónoma de Yucatán, Centro de Investigaciones Regionales Dr. Hideyo Noguchi, Merida, Yucatan, Mexico.ORCID https://orcid.org/0000-0002-3419-534X
Pablo Manrique-SaideUniversidad Autónoma de Yucatán, Unidad Colaborativa de Bioensayos Entomológicos (UCBE), Merida, Yucatan, Mexico.ORCID https://orcid.org/0000-0002-0565-1342
Fabián Correa-MoralesSecretaría de Salud México, Centro Nacional de Prevención y Control de Enfermedades (CENAPRECE), Mexico City, Mexico.ORCID https://orcid.org/0000-0002-6193-1242
Guadalupe Ayora TalaveraUniversidad Autónoma de Yucatán, Centro de Investigaciones Regionales Dr. Hideyo Noguchi, Merida, Yucatan, Mexico.ORCID https://orcid.org/0000-0002-2829-6945
Laura Conde-FerraezUniversidad Autónoma de Yucatán, Centro de Investigaciones Regionales Dr. Hideyo Noguchi, Merida, Yucatan, Mexico.ORCID https://orcid.org/0000-0002-8095-7106
Azael Che-MendozaUniversidad Autónoma de Yucatán, Unidad Colaborativa de Bioensayos Entomológicos (UCBE), Merida, Yucatan, Mexico.ORCID https://orcid.org/0000-0001-9954-3678
Jorge Palacio-VargasSecretaría de Salud México, Centro Nacional de Prevención y Control de Enfermedades (CENAPRECE), Mexico City, Mexico.
Rafael Valdez-VázquezSecretaría de Salud México, Centro Nacional de Prevención y Control de Enfermedades (CENAPRECE), Mexico City, Mexico.ORCID https://orcid.org/0000-0002-5026-9433
Julissa Guzman-HernandezSecretaría de Salud México, Centro Nacional de Prevención y Control de Enfermedades (CENAPRECE), Mexico City, Mexico.
Carlos Frederico Campelo de Albuquerque E MeloPan American Health Organization, Washington, DC, USA.ORCID https://orcid.org/0000-0003-0581-5535
Gonzalo Vazquez-ProkopecDepartment of Environmental Sciences, Emory University, Atlanta, Georgia, USA.ORCID https://orcid.org/0000-0002-0710-270X
Arbovirus Co-Circulation (ARCC) Research Consortium
Tetyana I VasylyevaJoe C. Wen School of Population and Public Health, University of California, Irvine, California, USA.ORCID https://orcid.org/0000-0002-9736-7022
Marina Escalera-Zamudio *Genetics Institute, University College London, London, United Kingdom.ORCID https://orcid.org/0000-0002-4773-2773
Miguel A Garcia-Knight *Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Mexico City, Mexico.ORCID https://orcid.org/0000-0001-9556-3719
Henry Puerta-Guardo *Universidad Autónoma de Yucatán, Centro de Investigaciones Regionales Dr. Hideyo Noguchi, Merida, Yucatan, Mexico.ORCID https://orcid.org/0000-0003-3050-4480

Funding

Wellcome Trust
6 · The paper itself

Abstract

Background: In 2013, chikungunya virus (CHIKV), a re-emerging Case Summary: In November 2025, a healthy adult male traveling from Cuba arrived in Merida, Mexico, and shortly after presented febrile symptoms consistent with an arboviral infection. CHIKV infection was diagnosed by RT-qPCR. Though the infection was mild, the patient developed a rash on the abdomen and neck that persisted for up to a month, with further inflammation of the joints of the left leg. Phylogenetic analysis of the viral genome indicated placement within the ECSA lineage, clustering with other contemporaneous virus genomes sampled from Brazil that belong to a recently described clade II within the country, in which viral genomes from Cuba also cluster. Conclusion: We identify a travel-associated ECSA lineage CHIKV case in Mexico. This viral lineage has not previously been detected in the country. This finding highlights the risk for subsequent local transmission and is consistent with reports of the presence of this lineage in Cuba. Ten years since the last CHIKV epidemic in Mexico, strengthened surveillance is required to anticipate potential local outbreaks within the region.

Indexed as

arboviruschikungunya virusECSAMexicophylogenetics

Identifiers

PMID42683070
PMCPMC13532220

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.