Evidence map›Paper›PMID 42682953›Full record

ArticleClinical case reports2026

A Challenging Case of Acute Methotrexate Toxicity.

Sahel Asgari, Narges Alizadeh, Shirin Zaresharifi, Mohaya Farzin

Abstract read
In one paragraph

Article in Clinical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sahel AsgariDepartment of Internal Medicine, School of Medicine Poursina Hospital, Guilan University of Medical Sciences Rasht Iran.ORCID https://orcid.org/0009-0008-1864-3203
Narges AlizadehDepartment of Dermatology, Skin Research Center Razi Hospital, School of Medicine, Guilan University of Medical Sciences Rasht Iran.
Shirin ZaresharifiDepartment of Dermatology, Skin Research Center Shahid Beheshti University of Medical Sciences Tehran Iran.ORCID https://orcid.org/0000-0003-4002-6953
Mohaya FarzinRazi Clinical Research Development Unit Razi Hospital, Guilan University of Medical Sciences Rasht Iran.ORCID https://orcid.org/0000-0003-4739-2454

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Catastrophic methotrexate toxicity, characterized by life-threatening pancytopenia and neutropenic enterocolitis, may occur even after a single low therapeutic dose, particularly in patients with renal impairment or dehydration. Early recognition and prompt multidisciplinary management are essential to improve outcomes.

Indexed as

drug eruptionmethotrexate toxicityneutropenic enter colitispancytopeniapsoriasis

Identifiers

PMID42682953
PMCPMC13530859

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.