Evidence map›Paper›PMID 42682949›Full record

ReviewFrontiers in neuroanatomy2026

Mapping the human thalamus: a historical review of thalamic atlases from histology to modern neuroanatomy.

Michelle Antonios, Gabor Szekely, Theofanis Karayannis, Andras Jakab

Abstract readReview
In one paragraph

Review in Frontiers in neuroanatomy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Michelle AntoniosLaboratory of Neural Circuit Assembly, Brain Research Institute, University of Zurich, Zurich, Switzerland.
Gabor SzekelyComputer Vision Laboratory, ETH Zurich, Zurich, Switzerland.
Theofanis KarayannisLaboratory of Neural Circuit Assembly, Brain Research Institute, University of Zurich, Zurich, Switzerland.
Andras JakabCenter for MR Research, University Children's Hospital Zurich, Zurich, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review outlines the development of thalamic atlases from early post-mortem 2D histological maps to modern 3D multimodal atlases used in neuroscience and clinical practice. Given the central role of the thalamus in sensory processing, movement, and cognition, accurate anatomical mapping has been essential for both research and neurosurgical targeting. By synthesizing historical and modern approaches, we highlight the methodological advances, such as the development of thalamus-specific MRI sequences, that have improved the precision of thalamic nuclei delineation. We focus on open-source atlases that support reproducible research and clinical applications. Future developments will likely focus on integrating multi-scale data; combining cytoarchitectonic, with quantitative MRI and computational models to improve thalamic parcellation and accurate localization

Indexed as

brain atlascytoarchitecturediffusion tractographyMRIthalamic nucleithalamus

Identifiers

PMID42682949
PMCPMC13530975

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.