Evidence map›Paper›PMID 42682824›Full record

SynthesisFrontiers in immunology2026

Natural killer cells in preeclampsia: an overview of current research.

Yuchao Zhang, Hang Su, Yipeng Zhang, Qichun Chen, Yuhan Meng, Cuijuan Zhang, Xuehui Bi, Qinghua Li, Weiwei Yang

Abstract readReviewSystematic Review
In one paragraph

Synthesis in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yuchao Zhang *Department of Obstetrics, Affiliated Hospital of Shandong Second Medical University, Weifang, China.
Hang Su *School of Life Science and Technology, Shandong Second Medical University, Weifang, China.
Yipeng ZhangSchool of Public Health, Shandong Second Medical University, Weifang, China.
Qichun ChenSchool of Life Science and Technology, Shandong Second Medical University, Weifang, China.
Yuhan MengCenter of Reproductive Medicine, Affiliated Hospital of Shandong Second Medical University, Weifang, China.
Cuijuan ZhangDepartment of Obstetrics, Affiliated Hospital of Shandong Second Medical University, Weifang, China.
Xuehui BiDepartment of Obstetrics, Affiliated Hospital of Shandong Second Medical University, Weifang, China.
Qinghua LiSchool of Public Health, Shandong Second Medical University, Weifang, China.
Weiwei YangDepartment of Obstetrics, Affiliated Hospital of Shandong Second Medical University, Weifang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Preeclampsia is a pregnancy disorder endangering maternal and fetal health, often accompanied by complications such as hypertension and proteinuria. Natural killer cells are indispensable in the occurrence and development of preeclampsia. Up to now, there has been no bibliometric study on NK cells and preeclampsia. Thus, we conducted a bibliometric analysis based on a systematic literature retrieval strategy. Methods: Publications related to NK cells and preeclampsia were retrieved from the Web of Science Core Collection and PubMed databases. CiteSpace and VOSviewer were applied to analyze publication trends, collaboration networks, co-citation patterns, and research hotspots. Results: The findings indicated that the prevailing research focal points in this domain predominantly encompass the maternal-fetal interface in preeclampsia, inflammatory mechanisms, immune mechanisms, and other related areas. Implantation, extracellular vesicles, and oxidative stress represent the emerging hotspots in this field in recent years. Conclusion: This study has systematically summarized the future trends in preeclampsia and natural killer cells research through bibliometrics, highlighted the current research frontiers and development trends, and provided valuable references for researchers in this field.

Indexed as

Killer Cells, NaturalPre-EclampsiaAnimalsBibliometricsFemaleHumansPlacentaPregnancybibliometricsmaternal‑fetal interfacenatural killer cellsplacentapreeclampsiatrophoblast

Identifiers

PMID42682824
PMCPMC13530010

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.