Evidence map›Paper›PMID 42682799›Full record

ArticleBiomedical reports2026

Contribution of platelet-rich plasma to the surgical treatment of rotator cuff tear: An experimental study.

Ioannis Angelos Trantos, Elias S Vasiliadis, Filippos S Giannoulis, Loukia Fragkopoulou, Spyros G Pneumaticos

Registry-linked trialAbstract read
In one paragraph

Article in Biomedical reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07689383 (The Contribution of Platelet-Rich Plasma to the Surgical Treatment of Rotator Cuff Tear), which is not on this map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07689383 phase2completednot on this map

The Contribution of Platelet-Rich Plasma to the Surgical Treatment of Rotator Cuff Tear: An Experimental Study

TypeinterventionalSponsorKAT General HospitalRan2021 to 2026Enrolled51ConditionsRotator Cuff Tear, Rotator Cuff Repair of the Shoulder, PRP InjectionArmsArthroscopic repair of shoulder rotator cuff tear, PRP injection
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ioannis Angelos TrantosSecond Department of Orthopaedic Surgery, Gennimatas General Hospital of Athens, 11527 Athens, Greece.
Elias S VasiliadisThird Department of Orthopaedic Surgery, University of Athens, KAT Hospital, 14561 Athens, Greece.
Filippos S GiannoulisHand, Upper Extremity and Microsurgery Department, 'Hygeia' Hospital, 15123 Athens, Greece.
Loukia FragkopoulouDepartment of Radiology, KAT Hospital, 14561 Athens, Greece.
Spyros G PneumaticosThird Department of Orthopaedic Surgery, University of Athens, KAT Hospital, 14561 Athens, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Shoulder rotator cuff tears are a common condition, which under specific indications is treated with arthroscopic repair. The optimal treatment aims at alleviating shoulder pain, the return of shoulder functionality and the prevention of recurrence of symptoms. The aim of the present study was to investigate and describe the augmentation of arthroscopic repair of rotator cuff tears with platelet-rich-plasma (PRP) treatment postoperatively, and its effects on pain, shoulder functionality and risk of retear. A total of 51 patients were divided into two groups. The treatment group received a subacromial PRP injection in the direct postoperative period after arthroscopic repair of rotator cuff tears, while the control group underwent arthroscopic treatment alone. There was no statistically significant difference in the verbal numeric rating score at 30 days postoperatively and the Constant-Murley and American Shoulder and Elbow Surgeons shoulder scores at 3, 6 and 12 months postoperatively between the two groups. However, the patients in the treatment group exhibited a statistically significant improvement of both scores between the 3- and 6-month timepoints, which was not observed in the control group. A smaller portion of the treatment group had rotator cuff retears compared with the control group (42.86 vs. 75.00%), although this was not statistically significant. It has not yet been adequately established that PRP treatment can provide additional benefits when combined with surgical treatment of rotator cuff tears. Further research with larger sample sizes may provide sufficient data concerning a possible protective effect on the postoperative retear risk. The trial has been registered on ClinicalTrials.gov under number NCT07689383 (submission date, July 1, 2026) and can be accessed at: clinicaltrials.gov/study/NCT07689383?term=NCT07689383&viewType=Card&rank=1.

Indexed as

arthroscopygrowth factorsPRProtator cuff tearsshoulder injuries

Identifiers

PMID42682799
PMCPMC13531125

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