ArticleFrontiers in cell and developmental biology2026
Dynamic junction remodeling and transient vascular disruption during cancer cell extravasation across the blood-brain barrier.
Article in Frontiers in cell and developmental biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Brain metastasis is the major cause of cancer-related mortality and remains a critical challenge in clinical oncology. Extravasation of circulating cancer cells across blood-brain barrier (BBB) is the first crucial and rate-limiting step for brain metastasis growth. However, the dynamic changes of brain endothelial cell junction and vascular integrity during cancer cell extravasation across BBB remains unclear. Here, we established a knockin zebrafish line,
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