SynthesisFrontiers in physiology2026
Effects of high-intensity interval training on cardiorespiratory fitness in adolescents with overweight or obesity: a systematic review and dose-response meta-analysis.
Synthesis in Frontiers in physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Corrections and comments
- Erratum issued
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Adolescents with overweight or obesity commonly exhibit reduced cardiorespiratory fitness (CRF), which is closely associated with cardiometabolic risk and premature mortality in adulthood. High-intensity interval training (HIIT) has been proposed as a time-efficient exercise strategy; however, quantitative evidence regarding the dose of HIIT in adolescents with overweight or obesity remains limited. Objective: This study aimed to evaluate the effects of HIIT on CRF in adolescents with overweight or obesity and to explore the nonlinear association between weekly HIIT dose and improvements in CRF using dose-response meta-analysis. Methods: PubMed, Embase, Web of Science, Scopus, and CNKI were searched from database inception to March 2026. Eligible studies were randomized controlled trials involving adolescents aged 10-18 years with overweight or obesity. Interventions consisted of structured HIIT or sprint interval training, and comparators included usual care, health education, or no additional structured exercise. The outcomes were VO Results: Sixteen randomized controlled trials, including 19 effect sizes were included. Compared with control conditions, HIIT significantly improved CRF (Hedges' g, 1.13, 95% CrI: 0.80-1.50). Exploratory subgroup analyses suggested more stable positive effects in studies using three sessions per week, a work-to-recovery ratio of approximately 1:1, and VO Conclusions: HIIT may be an effective strategy for improving CRF in adolescents with overweight or obesity. Its benefits appear to depend not only on the use of HIIT per se, but also on training frequency, work-recovery structure, and weekly dose. Current evidence suggests a possible nonlinear association between weekly HIIT dose and CRF improvement; however, this finding is hypothesis-generating rather than definitive and should be verified in larger trials with standardized HIIT prescription reporting, transparent dose coding, and longer follow-up. Systematic review registrations: https://www.crd.york.ac.uk/PROSPERO, identifier CRD420261392042.
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