Evidence map›Paper›PMID 42682636›Full record

ArticleAlzheimer's & dementia (Amsterdam, Netherlands)

Associations between lifestyle, genetic risk for Alzheimer's disease, and longitudinal brain atrophy in the UK Biobank (

Yating You, Laura M Lyall, Frederick K Ho, Claire E Hastie, Donald M Lyall

Abstract read
In one paragraph

Article in Alzheimer's & dementia (Amsterdam, Netherlands). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yating YouSchool of Health and Wellbeing University of Glasgow Glasgow Scotland UK.ORCID https://orcid.org/0000-0002-4014-9331
Laura M LyallSchool of Health and Wellbeing University of Glasgow Glasgow Scotland UK.
Frederick K HoSchool of Health and Wellbeing University of Glasgow Glasgow Scotland UK.
Claire E HastieSchool of Health and Wellbeing University of Glasgow Glasgow Scotland UK.
Donald M LyallSchool of Health and Wellbeing University of Glasgow Glasgow Scotland UK.

Funding

Wellcome Trust
6 · The paper itself

Abstract

introductionThe associations of modifiable daily lifestyle variables (e.g., smoking, diet, alcohol intake, sedentary behavior, and physical activity) with structural brain atrophy, and interaction with apolipoprotein E (

methodsAmong 3265 UK Biobank participants with repeated magnetic resonance imaging (MRI) data (mean follow-up 2.6 years), we assessed the relations between lifestyle,

resultsDISCUSSION: Our study reinforces the independent effect of

Indexed as

APOE ε4brain structurecohort studylifestylelongitudinal atrophy

Identifiers

PMID42682636
PMCPMC13529823

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.