Evidence map›Paper›PMID 42682575›Full record

ArticleFrontiers in artificial intelligence2026

Digital twin framework for personalized behavioral health optimization with Q-learning and graph-based planning.

Ayan Chatterjee, Nurilla Avazov

Abstract read
In one paragraph

Article in Frontiers in artificial intelligence, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ayan ChatterjeeDepartment of Digital Technology, NILU, Kjeller, Lillestrøm, Norway.
Nurilla AvazovInland School of Business and Social Sciences, University of Inland Norway, Lillehammer, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Promoting healthy lifestyle behaviors, including physical activity, sleep, diet, stress management, and healthy habits, requires adaptive systems capable of responding to dynamic changes in human behavior. Sustained behavioral change improves individual wellbeing, reduces disease risk, and contributes to healthier societies. However, developing personalized behavioral intervention systems is challenged by demographic heterogeneity, limited and fragmented datasets, reporting inconsistencies, and scarce high-quality labeled data. Ethical, privacy, and cost constraints further restrict the collection of large-scale longitudinal behavioral data. Consequently, there is a need for robust simulation and synthetic data generation frameworks that enable the development and evaluation of adaptive decision-making systems capable of optimizing personalized behavioral interventions over time. This study presents a digital twin framework integrated with tabular Q-learning for personalized behavioral recommendation under World Health Organization (WHO) lifestyle constraints. The framework combines synthetic behavioral data generation, reinforcement learning, and a TSP-inspired planning mechanism to investigate long-term behavioral adaptation in privacy-preserving simulated environments. The digital twin environment models user adherence variability, misreporting, dropout, and behavioral drift, enabling the evaluation of intervention strategies under realistic conditions. Experimental evaluation on synthetic populations demonstrates that Q-learning achieves competitive reward performance while maintaining favorable computational efficiency and stability compared with heuristic and reinforcement learning baselines. Statistical analysis indicates that reward differences among the evaluated methods are not significant; however, the proposed framework provides a flexible platform for adaptive behavioral recommendation and simulation-based experimentation. Furthermore, a real-time recommendation interface illustrates how simulation knowledge can be translated into actionable behavioral guidance. The proposed framework offers a scalable foundation for future digital health systems, particularly in scenarios where data scarcity, privacy constraints, and personalization requirements limit the use of real-world datasets.

Indexed as

behavior health optimizationdigital twinQ-learningrecommendation generationsimulation study

Identifiers

PMID42682575
PMCPMC13529758

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.