Evidence map›Paper›PMID 42682415›Full record

Trial reportFrontiers in endocrinology2026

Parathyroid autotransplantation into the brachioradialis protects parathyroid function during total thyroidectomy.

Shuang Wang, Yingming Liu, Gang Wu, Yuhan Gao, Huadong Qin, Chenlei Shi

Abstract readClinical Trial
In one paragraph

Trial report in Frontiers in endocrinology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shuang Wang *The Fourth Department of General Surgery, Second Affiliated Hospital, Harbin Medical University, Harbin, China.
Yingming Liu *The Fourth Department of General Surgery, Second Affiliated Hospital, Harbin Medical University, Harbin, China.
Gang WuThe Fourth Department of General Surgery, Second Affiliated Hospital, Harbin Medical University, Harbin, China.
Yuhan GaoThe Fourth Department of General Surgery, Second Affiliated Hospital, Harbin Medical University, Harbin, China.
Huadong QinThe Fourth Department of General Surgery, Second Affiliated Hospital, Harbin Medical University, Harbin, China.
Chenlei ShiThe Fourth Department of General Surgery, Second Affiliated Hospital, Harbin Medical University, Harbin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Surgery remains the foundation of differentiated thyroid cancer management. However, total thyroidectomy (TT) with lymph node dissection frequently predisposes patients to hypoparathyroidism (HypoPT). The sternocleidomastoid is the conventional site for parathyroid autotransplantation, but this approach cannot effectively assess graft viability and real-time functional monitoring. Methods: Two sequential experiments were conducted. In Experiment 1, graft survival criteria were established by analyzing serum parathyroid hormone (PTH) ratios in the bilateral cephalic veins among 30 controls and 100 patients undergoing brachioradialis parathyroid autotransplantation. In Experiment 2, 180 TT patients undergoing bilateral central neck dissection were allocated into three groups (60 per group): Results: In Experiment 1, bilateral PTH ratio ≤ 1.16 was defined as the physiological baseline, with ≥ 1.2-fold as the graft viability threshold, which showed superior 6-month survival vs the 1.5-fold standard (83% vs 74%, Conclusions: Brachioradialis parathyroid autotransplantation is safe and effective, while significantly reducing the risk of early postoperative HypoPT. Brachioradialis autotransplantation were recommended for compromised or inadvertently excised parathyroid glands. Clinical trial registration: https://www.chictr.org.cn/bin/home, identifier ChiCTR2400080970.

Indexed as

HypoparathyroidismParathyroid GlandsPostoperative ComplicationsThyroidectomyThyroid NeoplasmsAdultFemaleGraft SurvivalHumansMaleMiddle AgedParathyroid HormoneTransplantation, AutologousParathyroid Hormoneautotransplantationbrachioradialisparathyroidsurgerysurvival

Identifiers

PMID42682415
PMCPMC13529502

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.