Evidence map›Paper›PMID 42682394›Full record

ArticleHealth care science2026

Dietary Carotenoids and Cognitive Decline: A Longitudinal Study Among Chinese Middle-Aged and Older Adults.

Liyan Huang, Ting Shen, Minyu Wu, Yiying Gong, Gulisiya Hailili, Ziping Wang, Caifeng Zhao, Wei Chen, Shuang Rong, Changzheng Yuan

Abstract read
In one paragraph

Article in Health care science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Liyan HuangSchool of Public Health, the Second Affiliated Hospital Zhejiang University School of Medicine Hangzhou China.ORCID https://orcid.org/0000-0002-2649-3312
Ting ShenSchool of Public Health, the Second Affiliated Hospital Zhejiang University School of Medicine Hangzhou China.
Minyu WuSchool of Public Health, the Second Affiliated Hospital Zhejiang University School of Medicine Hangzhou China.
Yiying GongSchool of Public Health, the Second Affiliated Hospital Zhejiang University School of Medicine Hangzhou China.ORCID https://orcid.org/0009-0004-2846-4146
Gulisiya HaililiSchool of Public Health, the Second Affiliated Hospital Zhejiang University School of Medicine Hangzhou China.
Ziping WangDepartment of Clinical Nutrition, Division of Life Sciences and Medicine, The First Affiliated Hospital of USTC University of Science and Technology of China Hefei China.
Caifeng ZhaoSchool of Public Health, the Second Affiliated Hospital Zhejiang University School of Medicine Hangzhou China.
Wei ChenDepartment of Food Science and Nutrition, College of Biosystems Engineering and Food Science Zhejiang University Hangzhou China.
Shuang RongDepartment of Clinical Nutrition, Division of Life Sciences and Medicine, The First Affiliated Hospital of USTC University of Science and Technology of China Hefei China.ORCID https://orcid.org/0000-0002-2118-5732
Changzheng YuanSchool of Public Health, the Second Affiliated Hospital Zhejiang University School of Medicine Hangzhou China.ORCID https://orcid.org/0000-0002-2389-8752

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: This study examined the association between dietary intakes of total and specific carotenoids and cognitive decline among Chinese middle-aged and older adults. Methods: We included 4043 participants aged 55 years and older from the China Health and Nutrition Survey (1997-2006). Average daily dietary intakes of total carotenoids, α-carotene, β-carotene, β-cryptoxanthin, lycopene, and lutein + zeaxanthin were calculated from 3-day 24-h dietary recalls. Cognitive function was measured repeatedly using the Telephone Interview for Cognitive Status-Modified. Linear mixed-effects models were utilized to estimate beta coefficients ( Results: Higher intake of total dietary carotenoids was associated with slower cognitive decline. Comparing the top to bottom quintiles (median intake: 37.0 vs. 3.1 mg/day) of total carotenoids, the adjusted difference in annual decline rates (95% CI) was 0.018 (0.001-0.035, Conclusions: A potential nonlinear association between dietary carotenoids and cognitive decline was observed in Chinese middle-aged and older adults. Further research is warranted to confirm optimal intake level for dietary carotenoids and to investigate the underlying biological mechanisms.

Indexed as

Chinese middle‐aged and older adultcognitive declinedietary carotenoidprospective study

Identifiers

PMID42682394
PMCPMC13529439

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.