ArticleInternational journal of surgery (London, England)2026
The relationship between medication possession index and functional prognosis in patients with rheumatoid arthritis: a national longitudinal cohort study from CHARLS.
Article in International journal of surgery (London, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: To prospectively investigate the association between the Medication Possession Index (MPI) and the risk of incident functional dependence in middle-aged and older rheumatoid arthritis (RA) patients in China. Methods: This national longitudinal cohort study utilized data from the China Health and Retirement Longitudinal Study (CHARLS). A total of 2495 RA patients (mean age 67 · 5 ± 10 · 9 years; 36 · 5% male) without baseline functional dependence were included. MPI (range: 0-1), a composite, cross-sectional measure of pharmacotherapeutic coverage for 12 chronic conditions, was calculated at baseline. Complex survey weights were incorporated in all Cox models using survey::svycoxph(), and missing covariates were addressed via multiple imputation ( Results: Over 8530 person-years (median follow-up 3-4 years), 918 functional dependence events occurred (incidence rate: 10.8/100 person-years). Higher MPI quartiles were associated with higher functional independence survival (log-rank Conclusion: Higher MPI, reflecting better overall treatment coverage across multiple conditions, is independently associated with a reduced risk of functional dependence in middle-aged and older RA patients, showing a monotonic dose-response relationship. MPI shows potential as a pragmatic indicator of overall healthcare engagement for identifying high-risk patients who may benefit from interventions aimed at improving treatment coverage and health management.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.