Evidence map›Paper›PMID 42682288›Full record

ArticleInternational journal of surgery (London, England)2026

Impact of age on sex-related differences in outcomes after aneurysmal subarachnoid hemorrhage.

Xiuhu An, Shuai Zhou, Feng Guo, Wentao Dong, Yang Guo, Jiheng Hao, Xijin Wu, Long Zhao, Hao Zhang, Jian Li and 3 more

Abstract read
In one paragraph

Article in International journal of surgery (London, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Xiuhu AnDepartment of Neurosurgery, Tianjin Medical University General Hospital, Tianjin, China.
Shuai ZhouDepartment of Neurosurgery, The First People's Hospital of Yunnan Province, Kunming, China.
Feng GuoDepartment of Neurosurgery, Linyi People's Hospital, Linyi, China.
Wentao DongDepartment of Neurosurgery, Affiliated Jinhua Hospital, Zhejiang University School of Medicine, Jinhua, China.
Yang GuoDepartment of Anesthesiology, Tianjin Medical University General Hospital, Tianjin, China.
Jiheng HaoDepartment of Neurosurgery, Liaocheng People's Hospital, Liaocheng, China.
Xijin WuDepartment of Neurosurgery, Tianjin Medical University General Hospital, Tianjin, China.
Long ZhaoDepartment of Neurosurgery, Affiliated Hospital of North Sichuan Medical College, Sichuan, China.
Hao ZhangDepartment of Neurosurgery, Nanjing University Medical School Affiliated Nanjing Drum Tower Hospital, Nanjing, China.
Jian LiDepartment of Neurosurgery, Tianjin Medical University General Hospital, Tianjin, China.
Xinyu YangDepartment of Neurosurgery, Tianjin Medical University General Hospital, Tianjin, China.
Bangyue WangDepartment of Neurosurgery, The Second Affiliated Hospital of Anhui Medical University, Hefei, China.
Xiaoping TangDepartment of Neurosurgery, Affiliated Hospital of North Sichuan Medical College, Sichuan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Systematic investigations into the modifying effect of age on sex-related differences in postoperative outcomes after aSAH remain limited. This study aimed to clarify the role of age in the association between sex and poor outcomes. Methods: We retrospectively reviewed patients with aSAH who underwent surgical treatment and were consecutively admitted between January 2017 and December 2020 across 12 medical centers in four northern provinces of China. Multivariable logistic regression models were used to examine the association between sex and outcomes. Generalized additive models (GAMs) and segmented regression analyses were used to examine the nonlinear associations of sex and age with poor outcomes. Results: A total of 4865 patients were included in the analysis of sex and in-hospital outcomes, of whom 3979 completed follow-up and were included in the 2-year outcome analysis. Regarding 2-year outcomes, female patients exhibited significantly lower risks of poor outcomes (OR = 0.696, 95% CI: 0.564-0.859, Conclusion: Age-related sex differences influence the risk of poor outcomes after aSAH, highlighting the importance of considering sex-age interactions in clinical decision-making.

Indexed as

ageaneurysmal subarachnoid hemorrhagemortalityoutcomesexsurgical treatment

Identifiers

PMID42682288
PMCPMC13249240

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.