Evidence map›Paper›PMID 42682054›Full record

ArticleThe Canadian journal of urology2026

Autologous blood coagulum for fragment removal after ureteroscopic laser lithotripsy.

Tiffany R Huang, Bruce M Gao, Aymon Ali, Mariah C Hernandez, Christopher D Yang, Jonathan Badin-Castro, Carol Davis-Dao, Helen Gao, Seyedamirvala Saadat, Seyed Amiryaghoub M Lavasani and 5 more

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Article in The Canadian journal of urology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

15 authors.

Tiffany R HuangDepartment of Urology, University of California, Irvine, Orange, CA, USA.
Bruce M GaoDepartment of Urology, University of California, Irvine, Orange, CA, USA.
Aymon AliDepartment of Urology, University of California, Irvine, Orange, CA, USA.
Mariah C HernandezDepartment of Urology, University of California, Irvine, Orange, CA, USA.
Christopher D YangDepartment of Urology, University of California, Irvine, Orange, CA, USA.
Jonathan Badin-CastroDepartment of Urology, University of California, Irvine, Orange, CA, USA.
Carol Davis-DaoDepartment of Urology, University of California, Irvine, Orange, CA, USA.
Helen GaoDepartment of Urology, University of California, Irvine, Orange, CA, USA.
Seyedamirvala SaadatDepartment of Urology, University of California, Irvine, Orange, CA, USA.
Seyed Amiryaghoub M LavasaniDepartment of Urology, University of California, Irvine, Orange, CA, USA.
Sohrab N AliDepartment of Urology, University of California, Irvine, Orange, CA, USA.
Pengbo JiangDepartment of Urology, University of California, Irvine, Orange, CA, USA.
Roshan M PatelDepartment of Urology, University of California, Irvine, Orange, CA, USA.
Jaime LandmanDepartment of Urology, University of California, Irvine, Orange, CA, USA.
Ralph V ClaymanDepartment of Urology, University of California, Irvine, Orange, CA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUreteroscopy is the recommended surgical treatment for renal stones less than two centimeters in diameter but often leaves residual fragments, increasing the risk of stone recurrence. Autologous blood coagulum is a potential adjunct to ureteroscopy for aiding fragment retrieval. This study evaluates the efficacy and efficiency of autologous blood coagulum assisted ureteroscopy compared to ureteroscopy and basketing for achieving absolute stone-free Grade A status.

methodsFollowing Institutional Review Board approval, a retrospective review of our comprehensive UC Irvine Minimally Invasive Surgery Ureteroscopy database consisting of 962 patients undergoing ureteroscopy between 2018 to 2025 identified 15 renal units treated with ureteroscopy plus autologous blood coagulum and 47 matched controls treated with standard ureteroscopy and basketing alone. Primary outcomes included absolute stone-free status and stone-free rate, with operative time as a secondary outcome. Multivariate logistic regression was used to determine factors most closely associated with stone-free status.

resultsAutologous blood coagulum increased the proportion of patients achieving absolute stone-free Grade A status (60% vs. 19%; p = 0.007) and was associated with a greater odds of achieving Grade A status compared to standard ureteroscopy (OR = 4.6; 95% CI = 1.04-20.1; p = 0.044). In patients who received autologous blood coagulum, thulium laser use was associated with a significantly greater odds of achieving Grade A status (OR 6.7; 95% CI: 1.1-39; p = 0.047). There was no significant difference in the relative stone free rates for fragments ≤4 mm (Grades A+B+C) between groups (73% vs. 60%; p = 0.38). Mean operative time for autologous blood coagulum vs. the control group was comparable (141.1 vs. 135.1 min; p = 0.76).

conclusionsAutologous blood coagulum is an effective adjunctive technique to standard ureteroscopy that enhances stone-free outcomes without prolonging operative duration or requiring any additional equipment or expense.

Indexed as

Blood Transfusion, AutologousKidney CalculiLithotripsy, LaserUreteroscopyAdultFemaleHumansMaleMiddle AgedRetrospective StudiesTreatment OutcomeBlood coagulumresidual stonestone free rateureteroscopy

Identifiers

PMID42682054

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.