Evidence map›Paper›PMID 42681823›Full record

ArticleDiabetes, obesity & metabolism2026

Evaluation of Diabetes Risk Models Applied to the Prediction of Incident Dysglycaemia in African and European Populations.

Melony Fortuin-de Smidt, Patrik Wennberg, Hannah Maike Albers, Charles Agyemang, Felix P Chilunga, Rikard Landberg, Lisa K Micklesfield, Samuel N Darko, Julia Otten, Ellis Owusu-Dabo and 4 more

Abstract readEvaluation Study
In one paragraph

Article in Diabetes, obesity & metabolism, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Melony Fortuin-de SmidtDepartment of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.ORCID https://orcid.org/0000-0003-3488-7781
Patrik WennbergDepartment of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.
Hannah Maike AlbersHertz-Chair Innovation for Planetary Health, Transdisciplinary Research Area "Technology and Innovation for Sustainable Futures" and Center for Development Research (ZEF), University of Bonn, Bonn, Germany.
Charles AgyemangDepartment of Public and Occupational Health, Amsterdam Public Health Research Institute, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
Felix P ChilungaDepartment of Public and Occupational Health, Amsterdam Public Health Research Institute, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
Rikard LandbergDepartment of Life Sciences, Division of Food and Nutrition Science, Chalmers University of Technology, Gothenburg, Sweden.
Lisa K MicklesfieldSouth African Medical Research Council/WITS Developmental Pathways for Health Research Unit (DPHRU), Department of Paediatrics, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Samuel N DarkoDepartment of Molecular Medicine, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Julia OttenDepartment of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.
Ellis Owusu-DaboDepartment of Global and International Health, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Clemens WittenbecherDepartment of Life Sciences, Division of Food and Nutrition Science, Chalmers University of Technology, Gothenburg, Sweden.
Tommy OlssonDepartment of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.
Julia H GoedeckeDepartment of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.ORCID https://orcid.org/0000-0001-6795-4771
Ina DanquahDepartment of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.

Funding

European Research Area Personalised Medicine Joint Transnational Call ERA-PerMed JTC2022GSK Africa Non-Communicable Disease Open Lab ES/N013891/1Matilda Sjölund Diabetes FoundationRegion VästerbottenSciLifeLab & Wallenberg National Program for Data-Driven Life Sciences KAW 2020.0239South African Medical Research CouncilSouth African National Department of HealthSouth African National Research Foundation UID:99108Swedish Research Council Dnr: 2022-01529the Department of Science and Innovation, Bundesministerium für Bildung und ForschungThe European Research Council and Federal Ministry of Education and Researchthe UK Medical Research CouncilVINNOVA Dnr: 2022-00547
6 · The paper itself

Abstract

aimsWe evaluated overall and sex-specific performance of established diabetes risk models for predicting incident dysglycaemia in African and European populations. MATERIALS AND

methodsWe externally evaluated the African Diabetes Risk model, Finnish Diabetes Risk model, Epidemiological Study on the Insulin Resistance Syndrome model and the personal and clinical Framingham models. Evaluation was performed in three prospective cohorts: the Research on Obesity and Diabetes among African Migrants (RODAM-Pros; migrant and non-migrant Ghanaians; n = 1607), the Middle-aged Soweto cohort (MASC; urban Black South Africans; n = 515) and the Västerbotten Intervention Programme (VIP; Sweden; n = 3044). Dysglycaemia was defined according to American Diabetes Association criteria. Discrimination (c-statistic) and calibration were assessed before and after recalibration.

resultsDysglycaemia developed in 17.7% of RODAM-Pros participants, 35.0% of MASC participants and 27.5% of VIP participants, with median follow-up of 6.7, 6.7 and 9.9 years, respectively. All models demonstrated poor-to-modest discrimination (c-statistic < 0.7). Most models substantially underestimated risk. Recalibration eliminated systematic miscalibration and reduced calibration error to ≤ 2.3% in RODAM-Pros and VIP and ≤ 3.4% in MASC. Performance varied by sex and cohort.

conclusionsExisting diabetes risk prediction models can be applied to predict incident dysglycaemia in both Sub-Saharan African and European populations, but only after recalibration to local risk levels.

Indexed as

Diabetes Mellitus, Type 2AdultBlack PeopleEuropean PeopleFemaleHumansIncidenceMaleMiddle AgedProspective StudiesRisk AssessmentRisk FactorsSouth AfricaSouthern African PeopleSub-Saharan African PeopleSwedencalibrationdiscriminationethnicityincident dysglycaemiapredictionsub‐Saharan Africa

Identifiers

PMID42681823
PMCPMC13646359

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.