ArticleThe Journal of organic chemistry2026
Visible Light-Mediated Direct Decarboxylative Giese Amidations without a Photocatalyst─Batch and Flow.
Article in The Journal of organic chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
4 authors.
Funding
Abstract
Previous light-mediated approaches to the direct decarboxylative Giese amidation reaction relied on the use of costly, nonsustainable photocatalysts and faced challenges in efficient scale-up. We have successfully developed a photocatalyst-free, light-mediated methodology via a pathway that is thought to involve in situ EDA formation. The reaction is applicable in batch as well as under flow conditions, including efficient scale-up to gram scale in flow.
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Registered trials
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