Evidence map›Paper›PMID 42681694›Full record

ArticleJournal of animal science and biotechnology2026

Dietary green tea residue improves growth and antioxidant capacity via rumen microbiota and glutathione modulation in finishing beef cattle.

Changxiao Shi, Jiajie Deng, Hongliang Zhang, Yingqi Li, Shuo Zhang, Huili Wang, Shengnan Min, Yawen Luo, Zhihao Zhang, Jun Hao and 4 more

Abstract read
In one paragraph

Article in Journal of animal science and biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Changxiao ShiState Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, People's Republic of China.
Jiajie DengSchool of Agriculture and Environment, College of Sciences, Massey University, Palmerston, North, 4410, New Zealand.
Hongliang ZhangState Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, People's Republic of China.
Yingqi LiState Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, People's Republic of China.
Shuo ZhangState Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, People's Republic of China.
Huili WangState Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, People's Republic of China.
Shengnan MinState Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, People's Republic of China.
Yawen LuoState Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, People's Republic of China.
Zhihao ZhangState Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, People's Republic of China.
Jun HaoDepartment of Grassland Science, College of Animal Science, Guizhou University, Guiyang, 550025, People's Republic of China.
Yutao WangGuizhou Cattle Industry Group Co., Ltd., Guizhou, 550001, People's Republic of China.
Binghai CaoState Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, People's Republic of China.
Yang HeState Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, People's Republic of China.
Huawei SuState Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, People's Republic of China. suhuawei2016@cau.edu.cn.

Funding

China Agriculture Research Systems of MOF and MARA CARS-37the National Key R&D Program of China 2023YFD1300904
6 · The paper itself

Abstract

backgroundGreen tea residue (GTR) is an abundant by-product rich in polyphenols. This study aimed to investigate the effects of GTR on growth performance, rumen microbiota, and systemic metabolism in finishing beef cattle.

resultsForty-five 18‑month‑old finishing Angus steers with an average initial body weight of 474.44 ± 14.03 kg (mean ± SD) were individually housed and randomly assigned to three dietary treatments (n = 15 per group) using stratified randomization by initial body weight: control group (CG group, 150 g rice straw), low-dose GTR group (LG group, 75 g rice straw +75 g GTR), and high-dose GTR group (HG group, 150 g GTR). The feeding trial lasted 70 d with a 10-day adaptation period. To elucidate the regulatory mechanisms of GTR on beef cattle growth, we thoroughly assessed growth performance, nutrient digestibility, ruminal fermentation parameters, conducted bacterial 16S rRNA sequencing, analysed plasma biochemical and antioxidant markers, and executed an untargeted plasma metabolomic analysis. The LG group tended to increase average daily gain (ADG). Meanwhile, the LG group exhibited elevated plasma concentrations of β-hydroxybutyrate and glucose, increased activities of superoxide dismutase and glutathione S-transferase, an increased glutathione (GSH)/glutathione disulfide (GSSG) ratio, and reduced GSSG content. GTR treatment decreased reactive oxygen species and oxidative stress index. Furthermore, dietary GTR significantly modified the rumen microbial community structure, enriching Xylanibacter and Prevotellaceae_UCG-003, while reducing the abundance of Rikenellaceae_RC9_gut_group. Plasma metabolomics revealed that GTR treatment enriched GSH Metabolism and the Pentose Phosphate Pathway. Notably, gamma-glutamylcysteine was identified as a key mediator of the association between Xylanibacter and ADG in fattening beef cattle supplemented with GTR.

conclusionsDietary supplementation with 75 g/steer/d GTR improved growth performance and systemic antioxidant capacity in finishing beef cattle by modulating the rumen microbiota and activating the glutathione system. GTR represents a promising functional feed additive that simultaneously valorizes tea by‑products and enhances livestock productivity.

Indexed as

AntioxidantBeef cattleGlutathioneGreen tea residueGrowth performanceMicrobiome

Identifiers

PMID42681694
PMCPMC13536794

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.