ArticleMethods in molecular biology (Clifton, N.J.)2026
Methods to Examine Complement Activation by HIT Immune Complexes.
Article in Methods in molecular biology (Clifton, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Current assays for measuring complement activation by immune complexes (ICs) are largely indirect, non-specific, and employ non-physiologic conditions. To address these drawbacks, we developed methods for measuring the complement activating effects of ICs that cause heparin induced thrombocytopenia (HIT), a blood clotting disorder. These assays rely on the formation of in situ ICs in undiluted healthy donor plasma and/or whole blood as a physiologic source of complement. Once formed, complement-bound ICs in plasma or whole blood are detected using immunocapture and/or flow-based assays. While these methods are designed to study the complement activating properties of HIT ICs, the immunocapture and flow-based assays can be readily extended to other ICs of known composition.
Indexed as
Identifiers
42681413What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.