Evidence map›Paper›PMID 42681412›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2026

Mouse Models of Immune Thrombocytopenia.

Genevieve Marcoux, John W Semple, Rick Kapur, Johan Rebetz

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In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Genevieve MarcouxDivision of Hematology and Transfusion Medicine, Lund University, Lund, Sweden.
John W SempleDivision of Hematology and Transfusion Medicine, Lund University, Lund, Sweden. John_w.semple@med.lu.se.
Rick KapurSanquin Research, Department of Experimental Immunohematology, Amsterdam and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Johan RebetzDivision of Hematology and Transfusion Medicine, Lund University, Lund, Sweden. Johan.rebetz@med.lu.se.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is an extensive body of literature related to animal models of various immune thrombocytopenic conditions. These include those related to the autoimmune bleeding disorder immune thrombocytopenia (ITP), the alloimmune disorder of pregnancy, and the fetal and neonatal alloimmune thrombocytopenia (FNAIT). It appears that many of these models either confirm what has been found in the human disorders or, in some instances, are the first to describe a phenomenon related to immune thrombocytopenia that is of relevance in human medicine. These clinically relevant models will undoubtedly play a significant role in understanding the pathogenesis of the human disorders and the development of novel therapeutics. This chapter will describe the various animal models of ITP and FNAIT and the basic methodology on how to create them.

Indexed as

Disease Models, AnimalPurpura, Thrombocytopenic, IdiopathicThrombocytopenia, Neonatal AlloimmuneAnimalsFemaleHumansMicePregnancyActive ITPAnimal modelsFetal and neonatal thrombocytopeniaImmune thrombocytopenia (ITP)MethodologyPassive ITP

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.