Evidence map›Paper›PMID 42681401›Full record

Observational studyCanadian journal of anaesthesia = Journal canadien d'anesthesie2026

Phase-dependent agreement between noninvasive and invasive blood pressure monitoring during transcatheter aortic valve replacement: a prospective observational study.

Raffael Pereira Cezar Zamper, Ahmed Abdelaatti, Ricardo Hideo Tachibana, Luiz Guilherme Villares da Costa, Michael W A Chu, Rodrigo Bagur, Philip M Jones

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In one paragraph

Observational study in Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

7 authors.

Raffael Pereira Cezar ZamperDepartment of Anesthesia and Perioperative Medicine, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada. rzamper@uwo.ca.ORCID http://orcid.org/0000-0003-2783-3072
Ahmed AbdelaattiDepartment of Anesthesia and Perioperative Medicine, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.
Ricardo Hideo TachibanaDepartment of Anesthesia and Perioperative Medicine, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.
Luiz Guilherme Villares da CostaDepartment of Anesthesia, Hospital Israelita Albert Einstein, Sao Paulo, Brazil.
Michael W A ChuDivision of Cardiac Surgery, Department of Surgery, London Health Sciences Centre, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.
Rodrigo BagurDivision of Cardiology, Department of Medicine, Schulich School of Medicine and Dentistry, Western University, London Health Sciences Centre, London, ON, Canada.
Philip M JonesDepartment of Anesthesia, Mayo Clinic, Jacksonville, FL, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe aimed to evaluate the phase-dependent agreement between continuous noninvasive blood pressure monitoring using ClearSight™ (Edwards Lifesciences Corp., Irvine, CA, USA) and invasive arterial pressure (IAP) across distinct intraoperative phases of transcatheter aortic valve replacement (TAVR).

methodsWe conducted a single-centre observational study at a tertiary academic hospital performing TAVR. We included 21 patients undergoing TAVR, contributing 987 paired invasive and noninvasive blood pressure measurements. We recorded noninvasive blood pressure monitoring using ClearSight concurrently with standard IAP monitoring as part of routine clinical care. We analyzed repeated paired measurements using Bland-Altman methods extended with linear mixed-effects modeling, with additional sensitivity analyses performed to assess robustness.

resultsWe compared invasive and ClearSight-derived systolic, mean, and diastolic pressures. ClearSight underestimated systolic and mean pressures and overestimated diastolic pressure. After excluding outliers identified by quantile-quantile plot diagnostics, mean biases (IAP minus ClearSight) were +14 mm Hg (systolic), +6 mm Hg (mean), and -3 mm Hg (diastolic). Limits of agreement narrowed after outlier removal, and intraclass correlation coefficients improved (systolic, 0.69 to 0.72; mean, 0.65 to 0.68; diastolic, 0.59 to 0.63). Phase-specific analysis showed the widest disagreement during induction/stabilization, improved accuracy during valve deployment, and the best agreement, particularly for mean arterial pressure, after protamine administration, when vascular tone and hemodynamic stability were restored.

conclusionsClearSight showed phase-dependent agreement with IAP during TAVR, typically underestimating systolic and mean pressures, with improved agreement during hemodynamic stability, most notably after protamine. These findings support ClearSight as an adjunct rather than a replacement for invasive arterial monitoring during TAVR. Broader validation studies are warranted.

Indexed as

Blood Pressure DeterminationMonitoring, IntraoperativeTranscatheter Aortic Valve ReplacementAgedAged, 80 and overArterial PressureBlood PressureFemaleHumansMaleProspective StudiesBland–Altman analysisClearSight™hemodynamic monitoringintraoperative monitoringnoninvasive blood pressure monitoringtranscatheter aortic valve replacement

Identifiers

PMID42681401

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.