ArticleMethods in molecular biology (Clifton, N.J.)2026
Embryo Biopsy.
Article in Methods in molecular biology (Clifton, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
3 authors.
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Abstract
Trophectoderm (TE) biopsy is the preferred method for obtaining embryo specimens for preimplantation genetic testing (PGT). Containing approximately 5-10 cells, TE biopsies offer a stronger DNA amplification template, enhancing diagnostic accuracy and representing the whole embryo's chromosomal makeup better than single-cell biopsies. Performing TE biopsy demands advanced micromanipulation expertize. The procedure involves using laser technology alongside micromanipulation to separate the specimen from the blastocyst. Different methods can be employed based on the blastocyst's features and laboratory conditions. Biopsy tubing requires exceptional manual dexterity and coordination. Achieving an efficient PGT program relies on optimized blastocyst culture, biopsy, tubing techniques, and reliable cryopreservation processes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.