Evidence map›Paper›PMID 42681238›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2026

Retinal Degeneration and Regeneration in Xenopus laevis Tadpoles.

Jingxian Lun, Albert Chesneau, Caroline Borday, Muriel Perron

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jingxian LunUniversité Paris-Saclay, CNRS, Institut des Neurosciences Paris-Saclay, Saclay, France.
Albert ChesneauUniversité Paris-Saclay, CNRS, Institut des Neurosciences Paris-Saclay, Saclay, France.
Caroline BordayUniversité Paris-Saclay, CNRS, Institut des Neurosciences Paris-Saclay, Saclay, France. caroline.borday@universite-paris-saclay.fr.
Muriel PerronUniversité Paris-Saclay, CNRS, Institut des Neurosciences Paris-Saclay, Saclay, France. muriel.perron@universite-paris-saclay.fr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Xenopus laevis offers unique advantages for studying retinal regeneration due to its strong regenerative capacity and amenability to transgenesis and genome editing. We present a detailed protocol for inducing and monitoring rod photoreceptor degeneration and regeneration in Tg(rho:GFP-NTR) tadpoles, where nitroreductase expression under the rhodopsin promoter enables conditional and specific ablation of rods upon metronidazole exposure. In addition, we describe the generation of albino Tg(rho:GFP-NTR); tyr

Indexed as

RegenerationRetinaRetinal DegenerationXenopus laevisAnimalsAnimals, Genetically ModifiedCell ProliferationCRISPR-Cas SystemsEpendymoglial CellsLarvaMetronidazoleMonophenol MonooxygenaseNitroreductasesRetinal Rod Photoreceptor CellsRhodopsinMetronidazoleMonophenol MonooxygenaseNitroreductasesRhodopsinMüller cellsNitroreductase/metronidazole (NTR/MTZ) systemPhotoreceptor degenerationRegenerationRetinaXenopus laevis

Identifiers

PMID42681238

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.