ArticleNeuroImage2026
Associations between video gaming behaviors and cortical morphology in adolescents.
Article in NeuroImage, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
Abstract
Video gaming is highly prevalent in adolescence, yet its relationship with cortical morphology in early adolescence remains unclear. Data from the large, diverse nationwide Adolescent Brain Cognitive Development Study cohort (N = 5686) were analyzed to investigate the association between video gaming behaviors and cortical morphology in adolescents. Adolescents (mean: 14.2 years old) reported time spent playing single and multi-player games each day and their frequency of playing mature-rated games. Measures of cortical volume, surface area, and thickness of regions defined by the Desikan-Killiany atlas were obtained from 3T MRI scanners. Generalized additive mixed effects models were used to evaluate the association between gaming behaviors and cortical morphology, adjusting for demographics, genetic ancestry, socioeconomic status, non-gaming screen time, pubertal stage, body mass index percentile, scanner characteristics, and familial relationships. In addition to regional analysis, vertexwise analysis was performed using the Fast and Efficient Mixed Effects Algorithm, which provides higher spatial resolution. Higher total gaming time was associated with lower cortical surface area and thickness across multiple regions. Single-player but not multi-player gaming was associated with altered morphology in regions involved in language processing and social cognition, which may be due to the different processes engaged by each game type. Mature-rated gaming frequency was also associated with lower cortical thickness in several regions and lower surface area in the right parahippocampal gyrus. Our results demonstrate that different gaming behaviors are associated with distinct patterns of cortical morphology. Decreases in cortical surface area and thickness are a normative feature of adolescent development, and future research on long-term outcomes is required to determine whether these differences reflect variation outside of normative developmental trajectories and the directionality of this association.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.