Evidence map›Paper›PMID 42679489›Full record

ArticleClinics (Sao Paulo, Brazil)2026

Physical activity and cognitive performance: cross-sectional analysis of the Brazilian longitudinal study of adult health (ELSA-Brazil).

Amanda M Pádua, Claudia K Suemoto, Patrícia Fonseca Estrada, Marcos R N Cavalcante, Alessandra C Goulart, Paulo Andrade Lotufo, Itamar de Souza Santos, Isabela M Bensenor

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Article in Clinics (Sao Paulo, Brazil), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Amanda M PáduaFaculdade de Saúde Pública, Universidade de São Paulo, São Paulo, SP, Brazil.
Claudia K SuemotoDivision of Geriatrics, Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil.
Patrícia Fonseca EstradaFaculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil; Clinical and Epidemiological Research Center, University Hospital, Universidade de São Paulo, São Paulo, SP, Brazil. Electronic address: patricia.fonsecaestrada@gmail.com.
Marcos R N CavalcanteClinical and Epidemiological Research Center, University Hospital, Universidade de São Paulo, São Paulo, SP, Brazil.
Alessandra C GoulartDepartment of Epidemiology, Faculdade de Saúde Pública, Universidade de São Paulo, São Paulo, SP, Brazil.
Paulo Andrade LotufoClinical and Epidemiological Research Center, University Hospital, Universidade de São Paulo, São Paulo, SP, Brazil; Department of Internal Medicine, Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil.
Itamar de Souza SantosClinical and Epidemiological Research Center, University Hospital, Universidade de São Paulo, São Paulo, SP, Brazil; Department of Internal Medicine, Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil.
Isabela M BensenorClinical and Epidemiological Research Center, University Hospital, Universidade de São Paulo, São Paulo, SP, Brazil; Department of Internal Medicine, Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionEvidence on the relationship between Leisure-Time Physical Activity (LTPA), Commuting Physical Activity (CPA), and cognitive performance is inconsistent.

objectiveTo examine the associations between LTPA, CPA, and cognitive performance in adults from the Brazilian Longitudinal Study of Adult Health (ELSA‒Brazil).

methodsThis cross-sectional analysis included 13,340 participants (median age 51 years; 54.5% women). Physical Activity (PA) was assessed using the long-form International Physical Activity Questionnaire, including LTPA and CPA. Cognitive performance was measured by word memory, verbal fluency, and the Trail Making Test Part B. Z-scores were computed for each test, and a global cognitive score was derived as their mean. Linear regression models estimated associations between PA levels and cognitive performance after multivariable adjustment, including occupational status. Analyses were stratified by sex and conducted in the overall sample.

resultsLTPA inactivity was associated with lower scores for verbal fluency (β = -0.07; 95% CI: -0.10 to -0.04), executive function (β = -0.10; 95% CI: -0.13 to -0.06), and global cognition (β = -0.06; 95% CI: -0.08 to -0.03). CPA inactivity showed associations in the opposite direction, with higher executive function (β = 0.08; 95% CI: 0.05 to 0.12) and memory in men (β=0.05; 95% CI: 0.001 to 0.10). After adjustment for occupational status, CPA associations attenuated and lost significance.

conclusionIn this cross-sectional study, the relationship between PA and cognition differed by domain. LTPA was associated with better cognitive scores, while CPA showed non-favorable or null associations after adjustment.

Indexed as

Cognitive performanceCohort studiesCommuting physical activityLeisure-time physical activity

Identifiers

PMID42679489
PMCPMC13563223

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.