Evidence map›Paper›PMID 42678537›Full record

ArticlePediatric surgery international2026

Management and outcomes of congenital pulmonary airway malformations and bronchopulmonary sequestrations diagnosed in the fetal period.

Andrea L Corso, Isadora L Flores, Marina C Tonietto, Victorio S Boff, Luciano F Schopf, Paola B Isolan, Clarice B Giacomini, Jose A Magalhães, Jose Carlos Fraga

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Article in Pediatric surgery international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Andrea L CorsoNeonatology Service, Hospital de Clinicas de Porto Alegre (HCPA), Porto Alegre, Brazil.
Isadora L FloresSchool of Medicine, Luterana University of Brazil (ULBRA), Canoas, Brazil.
Marina C ToniettoSchool of Medicine, Caxias do Sul University of Brazil (UCS), Caxias do Sul, Brazil.
Victorio S BoffSchool of Medicine, Caxias do Sul University of Brazil (UCS), Caxias do Sul, Brazil.
Luciano F SchopfPediatric Surgery Service, Hospital de Clinicas de Porto Alegre (HCPA), Porto Alegre, Brazil.
Paola B IsolanPediatric Surgery Service, Hospital de Clinicas de Porto Alegre (HCPA), Porto Alegre, Brazil.
Clarice B GiacominiNeonatology Service, Hospital de Clinicas de Porto Alegre (HCPA), Porto Alegre, Brazil.
Jose A MagalhãesFetal Medicine Group, Gynecology and Obstetric Service, Hospital de Clinicas de Porto Alegre (HCPA), Porto Alegre, Brazil.
Jose Carlos FragaPediatric Surgery Service, Hospital de Clinicas de Porto Alegre (HCPA), Porto Alegre, Brazil. fraga.jcs@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo describe the prenatal and postnatal management and outcomes of fetuses prenatally diagnosed with congenital pulmonary airway malformation (CPAM) or bronchopulmonary sequestration (BPS).

methodsThis retrospective study included patients with a prenatal ultrasonographic diagnosis of CPAM or BPS who were treated at a quaternary referral hospital between January 2014 and December 2024.

resultsTwenty-seven fetuses were diagnosed with CPAM or BPS by prenatal ultrasonography. Five (18.5%) showed complete regression of the lesions during gestation. Among the 22 fetuses with persistent malformations at birth, 12 (54.5%) had left-lung malformations and 10 (45.5%) had right-lung malformations. At birth, 12 neonates (54.5%) were asymptomatic, and 10 (45.5%) had respiratory symptoms. Twenty patients underwent surgical resection of the lesion: 15 by thoracoscopy and five by open surgery. There were no deaths, and postoperative outcomes were excellent over a follow-up period of 18 (10-33.5) months.

conclusionPrenatal diagnosis of CPAM or BPS allows appropriate management of these malformations during gestation and after birth. Ultrasonographic follow-up throughout pregnancy is essential because lesions may either regress or increase in size and cause severe fetal complications. Surgical resection was performed in both symptomatic and asymptomatic children, with no deaths and excellent outcomes.

Indexed as

Bronchopulmonary SequestrationCystic Adenomatoid Malformation of Lung, CongenitalUltrasonography, PrenatalFemaleHumansInfant, NewbornPregnancyRetrospective StudiesTreatment OutcomeBronchopulmonary sequestrationCongenital pulmonary airway malformationFetusIntrauterine diagnosesPulmonary congenital malformations

Identifiers

PMID42678537
PMCPMC13534148

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