ArticleIrish journal of medical science2026
Prognostic nutritional index as a predictor of fetal growth restriction and adverse perinatal outcomes.
Article in Irish journal of medical science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFetal growth restriction (FGR) is a major cause of perinatal morbidity and mortality. Maternal nutritional and inflammatory status may play a role in its development. The Prognostic Nutritional Index (PNI), derived from serum albumin and lymphocyte count, reflects these pathways.
aimsTo investigate the association between maternal PNI and FGR and evaluate the predictive performance of first- and third-trimester PNI for FGR and adverse perinatal outcomes.
methodsThis retrospective study included 279 singleton pregnancies (151 FGR and 128 controls). FGR was defined as estimated fetal weight below the 3rd percentile. First- and third-trimester PNI values were calculated. Logistic regression identified independent predictors of FGR, and receiver operating characteristic analysis assessed predictive performance.
resultsFirst- and third-trimester PNI values were significantly lower in the FGR group than in controls (40.10 vs. 44.07, p<0.001; 37.09 vs. 38.36, p=0.002, respectively). Both first-trimester PNI (adjusted OR 0.80, 95% CI 0.73-0.87, p<0.001) and third-trimester PNI (adjusted OR 0.89, 95% CI 0.79-0.99, p=0.034) were independently associated with FGR. First-trimester PNI showed good predictive performance (AUC 0.76, 95% CI 0.70-0.81), with an optimal cut-off of ≤42.10 (70.9% sensitivity and 72.0% specificity), whereas third-trimester PNI showed lower accuracy (AUC 0.64, 95% CI 0.57-0.71). Lower third-trimester PNI was independently associated with preterm delivery among pregnancies complicated by FGR.
conclusionsMaternal PNI, particularly in the first trimester, was independently associated with FGR and may serve as a simple biomarker for early risk assessment.
Indexed as
Identifiers
42678506What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.