Evidence map›Paper›PMID 42678485›Full record

ArticleGeneral thoracic and cardiovascular surgery2026

Mid-term outcomes of xenopericardial roll graft replacement for thoracic and thoracoabdominal native aortic and prosthetic graft infection: a single-centre retrospective study.

Yusuke Inaba, Hidehito Endo, Yu Takahashi, Sachito Minegishi, Teppei Shimasaki, Daisuke Kurai, Harumasa Nakazawa, Norihiko Ohura, Hirohisa Takeuchi, Nobutsugu Abe and 1 more

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Article in General thoracic and cardiovascular surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Yusuke InabaDepartment of Cardiovascular Surgery, Kyorin University, 6-20-2, Shinkawa, Mitaka, Tokyo, 181-8611, Japan. inaba178yusuke@gmail.com.ORCID http://orcid.org/0000-0003-1357-0849
Hidehito EndoDepartment of Cardiovascular Surgery, Kyorin University, 6-20-2, Shinkawa, Mitaka, Tokyo, 181-8611, Japan.
Yu TakahashiDepartment of Cardiovascular Surgery, National Disaster Medical Center, Tokyo, Japan.
Sachito MinegishiDepartment of Cardiovascular Surgery, Kyorin University, 6-20-2, Shinkawa, Mitaka, Tokyo, 181-8611, Japan.
Teppei ShimasakiDepartment of Infectious Diseases, Kyorin University, Tokyo, Japan.
Daisuke KuraiDepartment of Infectious Diseases, Kyorin University, Tokyo, Japan.
Harumasa NakazawaDepartment of Anesthesiology, Tokyo Medical University, Tokyo, Japan.
Norihiko OhuraDepartment of Plastic and Reconstructive Surgery, Kyorin University, Tokyo, Japan.
Hirohisa TakeuchiDepartment of Gastrointestinal Surgery, Kyorin University, Tokyo, Japan.
Nobutsugu AbeDepartment of Gastrointestinal Surgery, Kyorin University, Tokyo, Japan.
Hiroshi KubotaDepartment of Cardiovascular Surgery, Kyorin University, 6-20-2, Shinkawa, Mitaka, Tokyo, 181-8611, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study aimed to evaluate the feasibility and mid-term outcomes of in situ aortic reconstruction using xenopericardial roll grafts for thoracic and thoracoabdominal native aortic and prosthetic graft infection.

methodsThis retrospective single-centre study included consecutive patients who underwent xenopericardial roll graft replacement, including branched graft reconstruction and/or tissue filling, between 2010 and 2024. A multidisciplinary treatment strategy was adopted.

resultsThis study included 21 patients who underwent 22 procedures (median age, 67 years; interquartile range, 63.75-73.75). On a procedure basis, the indications were infectious aortic aneurysm in 4 procedures and prosthetic graft infection in 18 procedures. Replacement sites included the ascending aorta (n = 4), aortic arch (n = 11), descending aorta (n = 6), and thoracoabdominal aorta (n = 1). Tissue filling was performed in 12 procedures. The 30-day and operative mortality rates were 13.6% (3/22) and 18.2% (4/22), respectively. After excluding the three procedures with 30-day mortality, 19 procedures were included in the Kaplan-Meier analyses. Aorta-related mortality occurred in 10.5% (2/19), both due to fungal reinfection. The median follow-up was 53.6 months (IQR, 20-80.5; maximum, 132 months). The estimated survival rates at 1, 3, 5, and 7 years were 94%±6%, 76%±11%, 70%±11%, and 56%±15%, respectively. Xenopericardial roll graft-related structural complications included suture-line pseudoaneurysm (n = 2), suture-line rupture (n = 1), branch kinking (n = 1), xenopericardial roll graft body pseudoaneurysm (n = 1), and proximal anastomotic pseudoaneurysm (n = 1). No thromboembolism or graft calcification was observed.

conclusionsXenopericardial roll graft replacement was technically feasible as part of a multidisciplinary staged strategy in selected patients with thoracic and thoracoabdominal native aortic or prosthetic graft infection. However, fungal reinfection and xenopericardial roll graft-related structural complications remain important concerns, and careful long-term surveillance is required. CLINICAL

trial registrationNot applicable. This study is a retrospective observational study.

Indexed as

Aortic infectionDeep sternal wound infectionGraft infectionXenopericardial roll graft replacementXenopericardium

Identifiers

PMID42678485

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.