Evidence map›Paper›PMID 42678450›Full record

SynthesisInternational ophthalmology2026

Efficacy of capsular bag fixation versus ciliary sulcus fixation IOL implantation in children patients: meta-analysis.

Yilin Wang, Zijie Zhou, Lingdan Wu, Yue Li, Hongfei Liao, Qihua Xu, Anan Wang

Abstract readComparative StudyMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in International ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yilin WangThe Affiliated Eye Hospital, Jiangxi Medical College, Nanchang University, No. 463 Bayi Avenue, Nanchang City, 330006, Jiangxi Province, China.
Zijie ZhouThe Affiliated Eye Hospital, Jiangxi Medical College, Nanchang University, No. 463 Bayi Avenue, Nanchang City, 330006, Jiangxi Province, China.
Lingdan WuThe Affiliated Eye Hospital, Jiangxi Medical College, Nanchang University, No. 463 Bayi Avenue, Nanchang City, 330006, Jiangxi Province, China.
Yue LiThe Affiliated Eye Hospital, Jiangxi Medical College, Nanchang University, No. 463 Bayi Avenue, Nanchang City, 330006, Jiangxi Province, China.
Hongfei Liao *The Affiliated Eye Hospital, Jiangxi Medical College, Nanchang University, No. 463 Bayi Avenue, Nanchang City, 330006, Jiangxi Province, China. liaohongfei6000@163.com.
Qihua Xu *The Affiliated Eye Hospital, Jiangxi Medical College, Nanchang University, No. 463 Bayi Avenue, Nanchang City, 330006, Jiangxi Province, China. xu7ganggang@163.com.
Anan Wang *The Affiliated Eye Hospital, Jiangxi Medical College, Nanchang University, No. 463 Bayi Avenue, Nanchang City, 330006, Jiangxi Province, China. wanganan6000@163.com.ORCID https://orcid.org/0000-0001-9020-8961

Funding

Jiangxi Health Commission No. 202610064Jiangxi Provincial Administration of Traditional Chinese Medicine No. 2025022432Special Project of Undergraduate Education and Teaching Reform Research of Nanchang University No. NCUJGLX-ZX2-2025-04
6 · The paper itself

Abstract

purposeTo systematically compare the safety and efficacy of ciliary sulcus versus capsular bag fixation in pediatric intraocular lens implantation.

methodsWe searched observational studies and RCTs in databases from inception until March 2025. Statistical analysis was performed using RevMan 5.4.

resultsEight studies (843 patients) were included. No significant differences were found in postoperative BCVA, spherical equivalent, visual axis opacity, or inflammation incidence (p > 0.05). Ciliary sulcus fixation showed a significantly higher risk of secondary glaucoma (RR = 0.43, 95%CI 0.20-0.96, p = 0.04). However, this finding was not robust in sensitivity analysis. In acquired cataract cases, myopic shift was more pronounced in the ciliary sulcus fixation group; worse visual outcomes were observed in the capsular bag fixation group among patients without amblyopia therapy. Uveitis incidence was higher in the ciliary sulcus group.

conclusionWhile both techniques show comparable efficacy, ciliary sulcus fixation significantly increases risks of secondary glaucoma and uveitis, and is associated with myopia progression. Capsular bag fixation is recommended as the preferred approach, with enhanced postoperative amblyopia treatment and long-term monitoring.

Indexed as

Ciliary BodyLens Capsule, CrystallineLens Implantation, IntraocularVisual AcuityChildChild, PreschoolHumansTreatment OutcomeCapsular bag fixationChildrenCiliary sulcus fixationComplicationsMeta-analysisVisual prognosis

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.