ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2026
Diagnostic utility of reticular iris pattern for identifying cytomegalovirus-associated Posner-Schlossman syndrome.
Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study aimed to evaluate the association between the reticular iris pattern and cytomegalovirus (CMV) positivity detected by aqueous humour polymerase chain reaction (PCR) testing in Posner-Schlossman syndrome (PSS) and to estimate its diagnostic performance.
methodsThirty patients with active PSS at a tertiary eye centre in Vietnam underwent aqueous humour polymerase chain reaction (PCR) testing and anterior segment assessment. Firth penalized logistic regression identified clinical signs associated with CMV positivity, and diagnostic performance metrics were calculated.
resultsCMV was detected in 46.7% (14/30) of cases. Reticular iris pattern was associated with CMV positivity (OR = 17.85, 95% CI 3.05-197.14, p < 0.001), present in 64% of CMV-positive versus 6% of CMV-negative cases, with 64.3% sensitivity, 93.8% specificity, and 90.0% positive predictive value. Stellate keratic precipitates were less sensitive but also associated with CMV (OR = 14.14, p = 0.027), demonstrating high specificity (100.0%, 95% CI 79.4%-100.0%). CMV-positive patients also showed higher rates of glaucomatous damage (85.7% vs. 18.8%, p < 0.001).
conclusionsReticular iris pattern demonstrated high specificity for CMV-associated PSS in our cohort. Recognition of this sign during slit-lamp examination may help prioritise aqueous PCR testing, but the sign should not replace virological confirmation. Validation in larger, prospective cohorts is warranted.
Indexed as
Identifiers
42678412What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.