Trial reportEuropean journal of trauma and emergency surgery : official publication of the European Trauma Society2026
Antegrade transcystic balloon dilatation in emergency laparoscopic cholecystectomy with MRCP validation.
Trial report in European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07490730 (Antegrade Transcystic Balloon Dilatation of the Papillary Sphincter During Emergency Laparoscopic Cholecystectomy for Common Bile Duct Stones), which is not on this map. Not yet cited in PubMed.
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The trial behind it
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Antegrade Transcystic Balloon Dilatation of the Papillary Sphincter During Emergency Laparoscopic Cholecystectomy for Common Bile Duct Stones: A Prospective Validation Study With Postoperative MRCP Confirmation
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Authors and funding
11 authors.
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Abstract
purposeEndoscopic retrograde cholangiopancreatography (ERCP) remains the predominant treatment of common bile duct stones but single-stage laparoscopic management via antegrade transcystic balloon dilatation (ATBD) offers a compelling alternative. All prior studies validate success solely by intraoperative fluoroscopic cholangiography, with no prospective trial employing postoperative magnetic resonance cholangiopancreatography (MRCP).
methodsThis single-centre prospective study enrolled 100 consecutive patients with confirmed CBD stones requiring emergency laparoscopic cholecystectomy (LC). ATBD was attempted in all patients. Primary outcome was MRCP-confirmed CBD stone clearance. Secondary outcomes included operative time and postoperative complications.
resultsOne hundred consecutive patients were enrolled (median age 69 years; 38% male; 56% ASA III-IV). ATBD was performed in 88 patients (88%). Postoperative MRCP was performed in 86 of 88 patients (98%), with residual stones identified in 24 (28%; 95% CI 19.5-38.2%), corresponding to an MRCP-confirmed CBD clearance rate of 72% (95% CI 61.8-80.5%). The median operative time was 90 min (IQR 75-111.5). Among the 88 patients who underwent ATBD, postoperative complications occurred in 12 (14%), most commonly pancreatitis (4.5%) and deep surgical site infection (4.5%); one patient died following severe post-procedural pancreatitis with multiorgan failure. The median hospital length of stay was 6 days (IQR 4-7.5).
conclusionPostoperative MRCP identified residual stones in 28% of patients who underwent MRCP, corresponding to an MRCP-confirmed clearance rate of 72%. These findings support the routine use of postoperative MRCP in post-procedural assessment for patients undergoing transcystic laparoscopic common bile duct exploration.
trial registrationNCT07490730, https://clinicaltrials.gov (registration date 16.03.2026).
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