Evidence map›Paper›PMID 42678188›Full record

ArticleMicrobiology spectrum2026

A novel

Tatsuro Hirayama, Natsume Kitahori, Mizuki Ishimine, NaNa Nakada, Yuya Ito, Naoki Iwanaga, Takahiro Takazono, Taiga Miyazaki, Koichi Izumikawa, Katsunori Yanagihara and 3 more

Abstract read
In one paragraph

Article in Microbiology spectrum, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Tatsuro HirayamaDepartment of Pharmacotherapeutics, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.ORCID 0000-0001-8554-3482
Natsume KitahoriDepartment of Pharmacotherapeutics, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
Mizuki IshimineDepartment of Pharmacotherapeutics, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
NaNa NakadaDepartment of Respiratory Medicine, Nagasaki University Hospital, Nagasaki, Japan.
Yuya ItoDepartment of Respiratory Medicine, Nagasaki University Hospital, Nagasaki, Japan.
Naoki IwanagaDepartment of Respiratory Medicine, Nagasaki University Hospital, Nagasaki, Japan.ORCID 0000-0002-0680-390X
Takahiro TakazonoDepartment of Infectious Diseases, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
Taiga MiyazakiDivision of Respirology, Rheumatology, Infectious Diseases, and Neurology, Department of Internal Medicine, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan.ORCID 0000-0002-0962-5758
Koichi IzumikawaDepartment of Infectious Diseases, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
Katsunori YanagiharaDepartment of Laboratory Medicine, Nagasaki University Hospital, Nagasaki, Japan.
Koichi MakimuraTeikyo University Institute of Medical Mycology, Teikyo University, Itabashi City, Tokyo, Japan.
Kazuhiro TsukamotoDepartment of Pharmacotherapeutics, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
Hiroshi MukaeDepartment of Respiratory Medicine, Nagasaki University Hospital, Nagasaki, Japan.ORCID 0000-0002-1429-5706

Funding

Japan Agency for Medical Research and Development JP26fk0108700Japan Society for the Promotion of Science 24K11656MSD Life Science Foundation, Public Interest Incorporated Foundation
6 · The paper itself

Abstract

Fosmanogepix (FMGX) is the prodrug of manogepix (MGX), which targets Gwt1, an inositol acyltransferase encoded by

Indexed as

Antifungal AgentsCandida aurisFungal ProteinsAmidinesAnimalsCandidiasisDrug Resistance, FungalMicrobial Sensitivity TestsMothsAmidinesAntifungal AgentsFungal ProteinsT-2307Candida aurisfosmanogepixGWT1manogepixTAC1B

Identifiers

PMID42678188
PMCPMC13688795

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.