ArticleAngewandte Chemie (International ed. in English)2026
Transformative Masked Ortho-Quinone Chemistry: From Direct Guaiacol Activation to Lignin-Based Adhesives.
Article in Angewandte Chemie (International ed. in English), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Guaiacol moieties (1-hydroxy-2-methoxy-benzenes) are among the most abundant structural motifs in renewable biophenolic feedstocks, representing a potential industrial-scale stream from softwood lignin through biorefinery valorization. Here, the transformative chemistry of masked ortho-quinones (MoQs) is introduced, yielding reactive guaiacol derivatives to enable thiol-guaiacol connectivity (TGC) polymers. Phenyliodine(III)diacetate (PIDA) oxidizes guaiacols to chemically pure MoQs within minutes at room temperature, generating activated triguaiacol monomers that undergo thiol-MoQ Michael-type polyaddition with multithiols. This bulk polymerization leads to TGC-adhesives, reaching professional performance lap-shear strengths up to 16.9 ± 0.9 MPa. The robust strategy is extended to directly activate technical lignin, generating curable multi-MoQ prepolymers which bond aluminum with lap-shear strengths of 9.1 ± 0.7 MPa, positioning MoQs as a sustainable platform chemistry to bridge from lignin to high-performance materials.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.