Evidence map›Paper›PMID 42677597›Full record

Trial reportDiabetes, obesity & metabolism2026

Evaluating Whole Fruit Feijoa Powder for Type 2 Diabetes Risk Prevention: A Randomised Controlled Trial.

I A Mohamed, I R Sequeira-Bisson, J J Lim, L D Plank, R Murphy, S D Poppitt, J L Miles-Chan

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Diabetes, obesity & metabolism, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Efficacy and Safety ofFoods (Basel, Switzerland) · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

I A MohamedHuman Nutrition Unit, School of Biological Sciences, Faculty of Science, University of Auckland, Auckland, New Zealand.ORCID https://orcid.org/0009-0005-6125-1481
I R Sequeira-BissonHuman Nutrition Unit, School of Biological Sciences, Faculty of Science, University of Auckland, Auckland, New Zealand.ORCID https://orcid.org/0000-0001-5414-9925
J J LimHuman Nutrition Unit, School of Biological Sciences, Faculty of Science, University of Auckland, Auckland, New Zealand.ORCID https://orcid.org/0000-0002-0861-9276
L D PlankDepartment of Surgery, University of Auckland, Auckland, New Zealand.ORCID https://orcid.org/0000-0003-2737-0151
R MurphyHigh Value Nutrition National Science Challenge, Auckland, New Zealand.ORCID https://orcid.org/0000-0002-0043-2423
S D PoppittHuman Nutrition Unit, School of Biological Sciences, Faculty of Science, University of Auckland, Auckland, New Zealand.ORCID https://orcid.org/0000-0002-2214-8378
J L Miles-ChanHuman Nutrition Unit, School of Biological Sciences, Faculty of Science, University of Auckland, Auckland, New Zealand.ORCID https://orcid.org/0000-0003-0313-7048

Funding

Ministry of Business, Innovation and Employment 3710040
6 · The paper itself

Abstract

backgroundLow energy diets (LEDs) are effective for body weight (BW) loss and improvement of type 2 diabetes (T2D) risk biomarkers. Emerging evidence suggests that whole fruit feijoa powder, rich in polyphenols and abscisic acid, may further support T2D prevention. The FERDINAND study investigated whether daily consumption of a whole fruit feijoa powder enhanced LED-driven improvements in fasting plasma glucose (FPG), BW, and other metabolic markers.

methodsAt in-clinic screening, 97 participants were enrolled into the trial and randomised to receive 1150 mg/day of whole fruit feijoa powder (Fx, n = 48) or Placebo treatment (n = 49) for 6 months. All participants underwent 2 months of LED-induced weight loss, followed by 4 months of dietary advice for weight loss maintenance. BW, FPG, and secondary outcomes including blood pressure (BP) were assessed at baseline (M0) and the end of months 2 (M2), 4 (M4), and 6 (M6). Data were analysed using linear mixed-effects models as intention-to-treat (ITT) with imputation for missing not-at-random data points.

resultsBW decreased in both treatment groups during the 2-month LED, with a gradual upward trajectory over the subsequent 4 months (time

conclusionsIn adults with overweight (predominantly obesity) and prediabetes, Fx supplementation may enhance blood pressure improvement achieved through BW loss. The polyphenolic matrix of whole fruit feijoa, which contains a high proportion of catechins, may have contributed to vascular benefits.

Indexed as

Diabetes Mellitus, Type 2FeijoaFruitPrediabetic StateAdultBlood GlucoseBlood PressureFemaleHumansMaleMiddle AgedPowdersWeight LossBlood GlucosePowdersabscisic acidblood pressurefeijoaFPGlow energy dietpolyphenolsprediabetestype 2 diabetes preventionweight loss

Identifiers

PMID42677597
PMCPMC13646332

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.