Evidence map›Paper›PMID 42677256›Full record

ArticleAdvanced functional materials2026

Shape-Programmable Particles from Photocurable Poly(β-Amino Esters) for Drug Delivery Applications.

Katherine A Trese, Kendra M Kreienbrink, Gavin J Channell, Ritu R Raj, Matthew M C Kwan, Courtney A Bailey, Ankit Gangrade, Hunter J Wiese, Jason A Burdick, C Wyatt Shields

Abstract read
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In one paragraph

Article in Advanced functional materials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Katherine A TreseDepartment of Chemical and Biological Engineering, University of Colorado Boulder.
Kendra M KreienbrinkMaterials Science and Engineering Program, University of Colorado Boulder.
Gavin J ChannellBiomedical Engineering Program, University of Colorado Boulder.
Ritu R RajDepartment of Chemical and Biological Engineering, University of Colorado Boulder.
Matthew M C KwanMaterials Science and Engineering Program, University of Colorado Boulder.
Courtney A BaileyBiomedical Engineering Program, University of Colorado Boulder.
Ankit GangradeDepartment of Chemical and Biological Engineering, University of Colorado Boulder.
Hunter J WieseDepartment of Chemical and Biological Engineering, University of Colorado Boulder.
Jason A BurdickDepartment of Chemical and Biological Engineering, University of Colorado Boulder.
C Wyatt ShieldsDepartment of Chemical and Biological Engineering, University of Colorado Boulder.

Funding

Adoptive Macrophage Transfers for Nanoparticle DeliveryR35GM147455 · NIGMS · UNIVERSITY OF COLORADO · PI Charles Wyatt Shields IV · 2022 to 2026
$2.0M
Interdisciplinary Bioengineering Research Training in DiabetesT32DK120520 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI Richard KP Benninger, KATHRYN M HASKINS · 2020 to 2026
$1.1M
FACSAria Fusion Cell SorterS10OD021601 · OD · UNIVERSITY OF COLORADO · PI LIU, XUEDONG · 2016 to 2016
$599k
NIDDK NIH HHS T32 DK120520NIGMS NIH HHS R35 GM147455NIH HHS S10 OD021601
6 · The paper itself

Abstract

Micro- and nanoparticle shape plays a critical role in their fate for drug delivery applications. However, few methods exist that enable the facile and scalable manufacturing of biodegradable particles with precise control over shape. To address this, photolithographic methods to fabricate particles from poly(β-amino esters) (PBAEs) are reported, where small changes to the prepolymer formulation result in diverse physical properties. By adjusting the molar ratio and chemical structure of component monomers, 1000-fold changes in elastic moduli and a range of degradation rates were readily achieved, all while retaining cytocompatibility. To explore the potential of this platform in a drug delivery context, particles were fabricated for two emerging biomedical applications in which shape is critical to function: discoidal cellular backpacks and helical magnetic microrobots. Using contact photolithography, rapid manufacturing (>10

Indexed as

cellular backpackDrug deliverymagnetic microrobotmicroparticlesnanoparticlesPBAEphotolithography

Identifiers

PMID42677256
PMCPMC13528665

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.