Evidence map›Paper›PMID 42677224›Full record

ArticleSexuality research & social policy : journal of NSRC : SR & SP2026

Work, Sex, and Substances: Differences in Self-Reported Chemsex Behaviors Between MSM Sex Workers and Digital Content Creators.

Kristopher Jackson, Martha Whitfield, Starr Tomlinson, Glenn-Milo Santos

Abstract read
In one paragraph

Article in Sexuality research & social policy : journal of NSRC : SR & SP, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kristopher JacksonCollege of Nursing & Health Sciences, University of Massachusetts Dartmouth, Dartmouth, MA, USA.ORCID 0000-0002-9887-0607
Martha WhitfieldCollege of Nursing & Health Sciences, University of Massachusetts Dartmouth, Dartmouth, MA, USA.ORCID 0000-0002-7631-9056
Starr TomlinsonUniversity of California San Francisco Medical Center, San Francisco, CA, USA.ORCID 0000-0001-6936-7204
Glenn-Milo SantosDepartment of Community Health Systems, School of Nursing, University of California San Francisco, San Francisco, CA, USA.ORCID 0000-0003-1009-5317

Funding

Virology CoreP30AI027763 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI STEVEN Grant DEEKS · 1988 to 2026
$93.6M
ASTERISK: Alcohol and Substance use Treatment and Engagement Research on Intervention Studies among Key populationsK24AA029958 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Glenn-Milo Santos · 2022 to 2026
$938k
NIAAA NIH HHS K24 AA029958NIAID NIH HHS P30 AI027763
6 · The paper itself

Abstract

Background: Chemsex, the use of psychoactive substances to enhance sexual activity, may vary by occupational context. This study compared its prevalence, substance-specific patterns, and acquisition behaviors among two groups: male sex workers who have sex with men (MSM) and MSM who create sexually explicit digital content. Methods: Cross-sectional web-based survey of HIV-negative U.S. MSM (N = 769) with verified platform profiles. Group differences were assessed using chi-square tests with Benjamini-Hochberg correction, and independent associations were examined using multivariable logistic regression. Results: Sex workers reported higher prevalence of criminalized or controlled psychoactive substance use in occupational contexts than digital content creators (47.7% vs. 21.6%), with occupational group emerging as the strongest independent predictor of use (aOR = 3.36, 95% CI 2.41-4.69). Sex workers also reported greater use of poppers and erectile dysfunction medications more frequently obtained through unregulated acquisition channels. Conclusions: Occupational context shapes distinct chemsex use profiles among MSM, underscoring the need for occupation sensitive harm reduction and clinical outreach. Policy Implications: MSM sex workers and digital content creators represent occupationally distinct populations with divergent substance use profiles. Harm reduction, clinical screening, and outreach should be tailored to the risk environments and substances characteristic of each group, rather than treating all MSM engaged in sexual labor as a single, undifferentiated population.

Indexed as

ChemsexDigital content creatorsMen who have sex with men (MSM)Sexualized drug useSex work

Identifiers

PMID42677224
PMCPMC13528647

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.