Evidence map›Paper›PMID 42677180›Full record

ReviewAdvances in orthopedics2026

Advancements in Surgical Management of Carpal Tunnel Syndrome: A Comparative Review of Open, Endoscopic, and Ultra-Minimally Invasive Techniques.

Nikeeta Nancoo, Ira Bhasin, Nasir Kharma, Yousef Al Shahomi, Amar Shamsah, Ezzeldin A Shalaby, Amanda Jane Abel, Aaron Samuel, Helal Salem Alhajri, Najeeb Ansari and 2 more

Abstract readReview
In one paragraph

Review in Advances in orthopedics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Nikeeta NancooSchool of Medicine, St. George's University, True Blue, Grenada, sgu.edu.ORCID https://orcid.org/0009-0005-2203-509X
Ira BhasinKasturba Medical College, Mangalore, India, kmc-mangalore.ORCID https://orcid.org/0009-0006-7287-6302
Nasir KharmaKing's College Hospital NHS Trust, London, UK.ORCID https://orcid.org/0009-0007-7936-2715
Yousef Al ShahomiSchool of Medicine and Dentistry, University of Lancashire, Preston, UK.ORCID https://orcid.org/0009-0007-7304-2622
Amar ShamsahUniversity of Calgary, Calgary, Alberta, Canada, ucalgary.ca.ORCID https://orcid.org/0009-0009-7896-8824
Ezzeldin A ShalabyFaculty of Medicine, Alexandria University, Alexandria, Egypt, alexu.edu.eg.ORCID https://orcid.org/0009-0007-2638-9877
Amanda Jane AbelPerdana University-Royal College Surgeons of Ireland, Kuala Lumpur, Malaysia.ORCID https://orcid.org/0009-0002-0597-0260
Aaron SamuelGeorgian National University SEU, Tbilisi, Georgia.ORCID https://orcid.org/0009-0004-4406-2032
Helal Salem AlhajriCollege of Medicine and Health Sciences, UAE University, Alain, UAE, uaeu.ac.ae.
Najeeb AnsariTexila American University, Georgetown, Guyana, tauedu.org.ORCID https://orcid.org/0009-0001-9786-5304
Bramaes DahalKathmandu Medical College, Kathmandu, Nepal, kmc.edu.np.ORCID https://orcid.org/0009-0007-3857-6661
Manju RaiShri Venkateshwara University, Gajraula, Uttar Pradesh, India, svu.edu.in.ORCID https://orcid.org/0009-0007-0627-3287

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Carpal tunnel syndrome (CTS) is the most common entrapment neuropathy, with surgical decompression as the definitive treatment for refractory or severe cases. With the evolution of surgical techniques, from open carpal tunnel release (OCTR) to endoscopic (ECTR) and ultra-minimally invasive ultrasound-guided approaches, there remains a need for a comprehensive comparative evaluation. This review aims to critically assess contemporary surgical modalities for CTS and to provide an evidence-based framework for patient-centered surgical decision-making. Methods: A structured narrative review was conducted using PubMed/MEDLINE, Scopus, Cochrane Library, and Web of Science, covering studies from 1985 to February 2026. Eligible studies included randomized controlled trials, cohort studies, systematic reviews, and meta-analyses reporting clinical outcomes of OCTR, ECTR, and ultrasound-guided techniques. Outcomes assessed included symptom relief, functional scores, complications, recurrence, return to work, and cost-effectiveness. Data were synthesized thematically due to heterogeneity. Results: OCTR and ECTR demonstrate comparable long-term symptom relief and functional outcomes. ECTR offers advantages in early postoperative recovery, including reduced pain and faster return to work. Ultra-minimally invasive ultrasound-guided techniques show promising early outcomes and accelerated recovery in selected patients, though long-term data remain limited. Complication rates are low across techniques and are influenced more by surgical expertise and completeness of release than by approach alone. Economic analyses suggest early recovery may offset higher procedural costs in working populations. Conclusion: Long-term outcomes of CTS surgery are broadly equivalent across techniques when adequate decompression is achieved. The surgical approach should be individualized based on disease severity, patient factors, occupational demands, and surgeon expertise. Further high-quality, long-term comparative studies are needed to define the role of emerging ultra-minimally invasive techniques.

Indexed as

carpal tunnel syndromeendoscopic carpal tunnel releasemedian nerve compressionminimally invasive surgeryopen carpal tunnel releaseultrasound-guided carpal tunnel release

Identifiers

PMID42677180
PMCPMC13528443

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.