ReviewFrontiers in sleep2026
A comprehensive review of sleep disordered breathing in people with congenital heart disease.
Review in Frontiers in sleep, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Introduction: Sleep disordered breathing (SDB) is known to be a comorbidity associated with congenital heart disease (CHD). This review evaluates the role of sleep disorders as a contributing factor to impairments in cardiovascular health, neurocognitive function, and health-related quality of life in individuals with CHD. Methods: A narrative review was conducted across PubMed, Ovid, and Cochrane Library (1990-2025) searches for studies cross-referencing "congenital heart disease" or "Fontan circulation" with sleep-related terms. Inclusion criteria were studies in CHD populations using objective or self-report sleep assessments; exclusions included non-English, non-original data, or conference abstracts. References of included articles were also screened to identify additional potentially relevant articles. Thirty three of 523 articles screened met inclusion criteria. Results: SDB is prevalent in both children and adults with CHD, with reported rates ranging from 31 to 63% in adults and up to 57% in children. Both obstructive and central sleep apnea are observed. Comorbid SDB is associated with increased inpatient mortality in infants, poorer quality of life in children and adults, neurocognitive impairments, and increased cardiovascular risk including arrhythmias and paradoxical emboli. Evidence for effective treatment remains limited, though lifestyle, behavioral, and ventilation strategies show potential benefit. Discussion: SDB is common in both children and adults with CHD and has a negative association with behavior, cognition and quality of life for people with CHD.
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Registered trials
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