Evidence map›Paper›PMID 42677096›Full record

ArticleNigerian medical journal : journal of the Nigeria Medical Association

Self-Medication Practices in Nigeria: A Systematic Review and Meta-Analysis.

Chibuzor G Muoka, Nnedimma V Akparanta, Favour A Taribo, Chiemela O Onubogu, David A Asiegbu, Chidubem J Azubike, Iheomachi O Nwokoro, Chukwuebuka E Athan, Ugwunna Ede, Emmanuel I Uwaechina

Abstract read
In one paragraph

Article in Nigerian medical journal : journal of the Nigeria Medical Association. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Self-Medication Practices in Nigeria: A Systematic Review and Meta-Analysis.Nigerian medical journal : journal of the Nigeria Medical Association
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Chibuzor G MuokaNnamdi Azikiwe University Teaching Hospital, Nnewi, Anambra State, Nigeria.
Nnedimma V AkparantaAbia State University Teaching Hospital, Aba, Abia State, Nigeria.
Favour A TariboAbia State University Teaching Hospital, Aba, Abia State, Nigeria.
Chiemela O OnuboguAbia State University Teaching Hospital, Aba, Abia State, Nigeria.
David A AsiegbuAbia State University Teaching Hospital, Aba, Abia State, Nigeria.
Chidubem J AzubikeAbia State University Teaching Hospital, Aba, Abia State, Nigeria.
Iheomachi O NwokoroAbia State University Teaching Hospital, Aba, Abia State, Nigeria.
Chukwuebuka E AthanAbia State University Teaching Hospital, Aba, Abia State, Nigeria.
Ugwunna EdeDavid Umahi Federal University of Health Sciences, Uburu, Ebonyi State, Nigeria.
Emmanuel I UwaechinaNnamdi Azikiwe University Teaching Hospital, Nnewi, Anambra State, Nigeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Self-medication is a common health-seeking practice in Nigeria and is associated with inappropriate medicine use, adverse drug reactions, and antimicrobial resistance. This systematic review and meta-analysis aimed to estimate the pooled prevalence of self-medication in Nigeria and synthesize evidence on its patterns, determinants, and consequences. Methodology: A systematic search of PubMed, Google Scholar, and African Journals Online (AJOL) was conducted for studies published between January 2000 and June 2025. Eligible studies reported self-medication practices among Nigerian populations. Study selection followed PRISMA guidelines, and methodological quality was assessed using the Mixed Methods Appraisal Tool. Random-effects meta-analysis using a generalized linear mixed model was performed to estimate pooled prevalence with 95% confidence intervals (CI). A prediction interval was computed to estimate the expected range of true prevalence in future similar studies. The review protocol was registered in PROSPERO (CRD420251130710). Results: Ninety-one studies involving 37,359 participants were included, with 86 contributing to the meta-analysis. The pooled prevalence of self-medication was 67.8% (95% CI: 63.0%-71.0%), with substantial heterogeneity (I Conclusion: Self-medication is highly prevalent in Nigeria, with widespread non-prescription antibiotic use contributing to antimicrobial resistance. Strengthening medicine regulation, improving healthcare access, expanding health insurance coverage, enhancing public education, and implementing antimicrobial stewardship programmes are essential to curb inappropriate self-medication and its consequences.

Indexed as

Antimicrobial resistanceDrug misuseNigeriaSelf-medication

Identifiers

PMID42677096
PMCPMC13527815

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.