Evidence map›Paper›PMID 42676937›Full record

Observational studyTurkish journal of medical sciences2026

Evaluation of acne vulgaris patient care in outpatient clinics: guideline adherence and patient education.

Mefküre Durmuş, Betül Sena Çavdar, İbrahim Etem Arica, Sena Ustaömer, Sena Güzel Karahan, Seçil Çolak, Selcen Şenol

Abstract readObservational Study
In one paragraph

Observational study in Turkish journal of medical sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mefküre DurmuşDepartment of Clinical Pharmacy, Faculty of Pharmacy, Karadeniz Technical University, Trabzon, Turkiye.ORCID https://orcid.org/0000-0001-9745-4196
Betül Sena ÇavdarFaculty of Pharmacy, Karadeniz Technical University, Trabzon, Turkiye.ORCID https://orcid.org/0009-0006-0510-7714
İbrahim Etem AricaDepartment of Dermatology and Venerology, Faculty of Medicine, Karadeniz Technical University Trabzon, Turkiye.ORCID https://orcid.org/0000-0003-2733-2534
Sena UstaömerDepartment of Clinical Pharmacy, Faculty of Pharmacy, Karadeniz Technical University, Trabzon, Turkiye.ORCID https://orcid.org/0000-0002-8701-3802
Sena Güzel KarahanDepartment of Clinical Pharmacy, Faculty of Pharmacy, İnönü University, Malatya, Turkiye.ORCID https://orcid.org/0000-0003-0818-2665
Seçil ÇolakDepartment of Dermatology and Venerology, Faculty of Medicine, Karadeniz Technical University Trabzon, Turkiye.ORCID https://orcid.org/0009-0000-9390-1569
Selcen ŞenolDepartment of Physical Medicine and Rehabilitation, Garnet Health Medical Center, New York, NY, USA.ORCID https://orcid.org/0009-0005-6212-9007

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background/aim: Acne vulgaris, affecting over 85% of adolescents, is the most prevalent chronic inflammatory skin disorder. Its management is severity-based, with specific drug selections and combinations according to guidelines. However, adherence to these guidelines and the adequacy of patient counseling remain uncertain in real-world practice. The aim in this study was to evaluate prescribing patterns in acne management, assess compliance with guidelines, and promote awareness among healthcare professionals. Materials and methods: A prospective observational study was conducted in the dermatology outpatient clinic of a tertiary hospital in Türkiye between February and May 2025. Demographic and clinical data were collected, and acne severity was graded according to the Türkiye Dermatology Association (TDA) criteria. Prescriptions were evaluated for guideline concordance with American Dermatology Association (ADA) 2016/2024, National Institute for Health and Care Excellence (NICE) 2021, and TDA 2018. Potential drug-drug interactions and the adequacy of clinical teaching for acne medication were also assessed through a multidisciplinary evaluation. Statistical analyses were performed using descriptive methods, the Kruskal-Wallis test, Pearson's chi-squared test, and Fisher's exact test, as appropriate. Results: Oral isotretinoin, topical retinoids, and topical antibiotics were the most frequently prescribed agents. While isotretinoin use was largely appropriate, deviations from guideline recommendations, particularly oral antibiotic monotherapy, were observed. Some drug-drug interactions and limitations in structured patient counseling were also identified. Among the clinical guidelines, adherence was highest to the ADA guidelines, followed by the TDA guidelines. Moreover, the severity of the disease appeared to influence which guideline was followed. Conclusion: Although treatment largely followed severity-based recommendations, gaps in guideline adherence and patient education highlight the need for improved prescribing practices and interprofessional collaboration in acne management.

Indexed as

Acne VulgarisGuideline AdherencePatient Education as TopicPractice Patterns, Physicians'AdolescentAdultAmbulatory Care FacilitiesAnti-Bacterial AgentsDermatologic AgentsFemaleHumansIsotretinoinMaleProspective StudiesYoung AdultAnti-Bacterial AgentsDermatologic AgentsIsotretinoinacne vulgarisAntiacne medicationguideline adherenceisotretinoinpatient education

Identifiers

PMID42676937
PMCPMC13528750

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.