Evidence map›Paper›PMID 42676927›Full record

ArticleRevista panamericana de salud publica = Pan American journal of public health2026

Transforming pediatric oncology in Ecuador through the Global Platform for Access to Childhood Cancer Medicines.

Marmol Lissette, Liliana Vásquez, Carmen Guerrero, Nilda Villacrés, Daniel A Antiporta, Manuel Lavayen, Karina Meza, Paola Solís, David Santana, Ricardo Solís and 19 more

Abstract read
In one paragraph

Article in Revista panamericana de salud publica = Pan American journal of public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors.

Marmol LissetteNational Directorate for Strategies on the Prevention and Control of Noncommunicable Diseases, Mental Health, and the Socioeconomic Phenomenon of Drugs Ministry of Public Health Quito Ecuador National Directorate for Strategies on the Prevention and Control of Noncommunicable Diseases, Mental Health, and the Socioeconomic Phenomenon of Drugs, Ministry of Public Health, Quito, Ecuador.
Liliana VásquezDepartment of Noncommunicable Diseases and Mental Health Pan American Health Organization Washington, DC United States of America Department of Noncommunicable Diseases and Mental Health, Pan American Health Organization, Washington, DC, United States of America.
Carmen GuerreroDepartment of Noncommunicable Diseases and Mental Health Pan American Health Organization Quito Ecuador Department of Noncommunicable Diseases and Mental Health, Pan American Health Organization, Quito, Ecuador.
Nilda VillacrésDepartment of Noncommunicable Diseases and Mental Health Pan American Health Organization Quito Ecuador Department of Noncommunicable Diseases and Mental Health, Pan American Health Organization, Quito, Ecuador.
Daniel A AntiportaDepartment of Noncommunicable Diseases and Mental Health Pan American Health Organization Quito Ecuador Department of Noncommunicable Diseases and Mental Health, Pan American Health Organization, Quito, Ecuador.
Manuel LavayenRegional Revolving Funds Pan American Health Organization Washington, DC United States of America Regional Revolving Funds, Pan American Health Organization, Washington, DC, United States of America.
Karina MezaNational Directorate of Hospitals Ministry of Public Health Quito Ecuador National Directorate of Hospitals, Ministry of Public Health, Quito, Ecuador.
Paola SolísNational Directorate of Medicines and Medical Devices Ministry of Public Health Quito Ecuador National Directorate of Medicines and Medical Devices, Ministry of Public Health, Quito, Ecuador.
David SantanaNational Directorate of Comprehensive Health Care Ministry of Public Health Quito Ecuador National Directorate of Comprehensive Health Care, Ministry of Public Health, Quito, Ecuador.
Ricardo SolísPediatric Oncohematology Department Baca Ortiz Hospital Quito Ecuador Pediatric Oncohematology Department, Baca Ortiz Hospital, Quito, Ecuador.
María Del Carmen TrujilloClinical Oncohematology Department Eugenio Espejo Hospital Quito Ecuador Clinical Oncohematology Department, Eugenio Espejo Hospital, Quito, Ecuador.
Gema SolórzanoPediatric Oncohematology Department Portoviejo Specialty Hospital Manabí Ecuador Pediatric Oncohematology Department, Portoviejo Specialty Hospital, Manabí, Ecuador.
Lorena SánchezClinical Oncohematology Department Abel Gilbert Pontón Specialty Hospital Guayaquil Ecuador Clinical Oncohematology Department, Abel Gilbert Pontón Specialty Hospital, Guayaquil, Ecuador.
Doris CallePediatric Oncohematology Department Icaza Bustamante Hospital Guayaquil Ecuador Pediatric Oncohematology Department, Icaza Bustamante Hospital, Guayaquil, Ecuador.
Diana BonillaPediatric Oncohematology Department Icaza Bustamante Hospital Guayaquil Ecuador Pediatric Oncohematology Department, Icaza Bustamante Hospital, Guayaquil, Ecuador.
Gissela SanchezPediatric Oncohematology Department Hospital Sociedad de Lucha contra el Cancer (SOLCA) Quito Ecuador Pediatric Oncohematology Department, Hospital Sociedad de Lucha contra el Cancer (SOLCA) Quito, Ecuador.
Luis EspinPediatric Oncohematology Department Hospital SOLCA Guayaquil Ecuador Pediatric Oncohematology Department, Hospital SOLCA Guayaquil, Ecuador.
Enmanuel GuerreroPediatric Oncohematology Department Hospital SOLCA Cuenca Ecuador Pediatric Oncohematology Department, Hospital SOLCA Cuenca, Ecuador.
Richar CedeñoPediatric Oncohematology Department Hospital SOLCA Manabí Ecuador Pediatric Oncohematology Department, Hospital SOLCA Manabí, Ecuador.
Soledad JimenezPediatric Oncohematology Department Hospital SOLCA Loja Ecuador Pediatric Oncohematology Department, Hospital SOLCA Loja, Ecuador.
Araceli MoralesDepartment of Noncommunicable Diseases and Mental Health World Health Organization Geneva Switzerland Department of Noncommunicable Diseases and Mental Health, World Health Organization, Geneva, Switzerland.
Toby KasperDepartment of Pediatric Medicine St. Jude Children's Research Hospital Memphis, TN United States of America Department of Pediatric Medicine, St. Jude Children's Research Hospital, Memphis, TN, United States of America.
Santiago MillanDepartment of Noncommunicable Diseases and Mental Health World Health Organization Geneva Switzerland Department of Noncommunicable Diseases and Mental Health, World Health Organization, Geneva, Switzerland.
Pablo AlcocerRegional Revolving Funds Pan American Health Organization Washington, DC United States of America Regional Revolving Funds, Pan American Health Organization, Washington, DC, United States of America.
Christopher LimRegional Revolving Funds Pan American Health Organization Washington, DC United States of America Regional Revolving Funds, Pan American Health Organization, Washington, DC, United States of America.
Mauricio MazaDepartment of Noncommunicable Diseases and Mental Health Pan American Health Organization Washington, DC United States of America Department of Noncommunicable Diseases and Mental Health, Pan American Health Organization, Washington, DC, United States of America.
Silvana LucianiDepartment of Noncommunicable Diseases and Mental Health Pan American Health Organization Washington, DC United States of America Department of Noncommunicable Diseases and Mental Health, Pan American Health Organization, Washington, DC, United States of America.
Carlos Rodríguez-GalindoDepartment of Pediatric Medicine St. Jude Children's Research Hospital Memphis, TN United States of America Department of Pediatric Medicine, St. Jude Children's Research Hospital, Memphis, TN, United States of America.
Sonia QuezadaDepartment of Noncommunicable Diseases and Mental Health Pan American Health Organization Quito Ecuador Department of Noncommunicable Diseases and Mental Health, Pan American Health Organization, Quito, Ecuador.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Childhood cancer survival exceeds 80% in high-income countries but remains below 50% across much of Latin America. In Ecuador, limited access to diagnosis and essential medicines, and fragmented governance have hindered progress. In 2025, Ecuador became the first country in the Region of the Americas to implement the Global Platform for Access to Childhood Cancer Medicines, an initiative led by the World Health Organization (WHO) and St. Jude Children's Research Hospital to ensure equitable access to quality medicines while strengthening health systems. Methods: Between 2023 and 2025, Ecuador's Ministry of Public Health, the Pan American Health Organization (PAHO), WHO and St. Jude codesigned a participatory implementation plan. A national situational analysis guided the 2024-2026 roadmap and focused on governance, regulatory alignment, supply-chain optimization and workforce capacity. Key operational tools included medicine forecasting and quantification methodologies, developing standardized treatment protocols, and coordinating with the immunization program's cold-chain infrastructure. Results: The initiative catalyzed the creation of the National Commission for Childhood and Adolescent Cancer, integration of all prioritized oncology medicines into the national formulary, and consensus in national treatment protocols. Strengthened logistics reduced delivery times for medicines to less than 96 hours, and chemotherapy management training established a foundation for continuing education. Ecuador became the first country in the Region to receive medicines for childhood cancer procured through the Global Platform. Conclusions: Implementation of the Global Platform in Ecuador has strengthened pediatric oncology and positioned it as a national health priority. By coupling medicine access with systemic reform, Ecuador has demonstrated that collaborative governance, intersectoral coordination and political commitment can build sustainable capacity to deliver equitable childhood cancer care.

Indexed as

childrenDrug chronotherapyEcuadorhealth policy, planning and managementneoplasms

Identifiers

PMID42676927
PMCPMC13528676

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.