Evidence map›Paper›PMID 42676892›Full record

ReviewFrontiers in molecular biosciences2026

The function of phosphoglycerate mutase 1 (PGAM1) and its role in diseases.

Aihong Peng, Junqin Li, Huifang Liang, Yuanjun Yao, Kaiming Zhang

Abstract readReview
In one paragraph

Review in Frontiers in molecular biosciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Aihong PengShanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan Central Hospital, Taiyuan, China.
Junqin LiShanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan Central Hospital, Taiyuan, China.
Huifang LiangShanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan Central Hospital, Taiyuan, China.
Yuanjun YaoShanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan Central Hospital, Taiyuan, China.
Kaiming ZhangShanxi Key Laboratory of Stem Cells for Immunological Dermatosis, State Key Breeding Laboratory of Stem Cells for Immunological Dermatosis, Institute of Dermatology, Taiyuan Central Hospital, Taiyuan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phosphoglycerate mutase 1 (PGAM1) is a pivotal metabolic enzyme during the process of glycolysis, catalyzing the interconversion between 3-phosphoglycerate and 2-phosphoglycerate. PGAM1 is mainly involved in cellular energy metabolism and biosynthesis, it is generally upregulated in numerous human cancers and promotes cell proliferation, invasion, and drug resistance. It serves as a significant biomarker for tumor diagnosis and a potential therapeutic target. In this paper, the basic structure and functions of PGAM1 and its family members, metabolic, non-metabolic activity and the regulatory mechanisms of PGAM1 and its correlation with diseases, as well as the latest progress of PGAM1 inhibitors in tumor diagnosis and treatment are introduced, aiming to provide new ideas for the targeted therapy of related diseases.

Indexed as

diseasesinhibitorsmetabolicnon-metabolicPGAM1

Identifiers

PMID42676892
PMCPMC13527375

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.