Trial reportFrontiers in dental medicine2026
Comparison of the efficacy of placental extract gel vs. curcumin gel in the treatment of oral aphthous ulcer: a randomized clinical trial.
Trial report in Frontiers in dental medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Context: Canker sores are among the most common oral mucosal lesions with an unclear etiology. Recurrent aphthous stomatitis (RAS) causes considerable pain and discomfort, affecting quality of life. Aim: To compare the efficacy of placental extract gel (PEG) and curcumin gel in the management of recurrent aphthous stomatitis. Settings and design: A randomized clinical trial conducted in the Department of Public Health Dentistry. Methods and material: Thirty participants diagnosed with RAS were randomly allocated into two groups: Group I (PEG, Statistical analysis: An independent Results: Both groups showed significant reductions in ulcer size and pain scores by day 3 and day 7 ( Conclusion: Both placental extract gel and curcumin gel were effective in reducing pain and ulcer size in recurrent aphthous stomatitis. Placental extract gel demonstrated lower recurrence rates compared with curcumin gel. No adverse effects were observed in either group; however, this study was not powered to detect differences in safety outcomes. Clinical Trial Registration: https://trialsearch.who.int/Trial2.aspx?TrialID=CTRI/2023/11/059637, Identifier: CTRI/2023/11/059637.
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